Hickman M S, Schwesinger W H, Page C P
Department of Surgery, University of Texas Health Science Center, San Antonio.
Arch Surg. 1988 Apr;123(4):409-11. doi: 10.1001/archsurg.1988.01400280015001.
The influence of diabetes on the risks associated with the operative treatment of acute cholecystitis has not been clearly defined. Therefore, a case-control study of 72 diabetics requiring urgent operation for acute cholecystitis was undertaken. Patients were matched for age, gender, and date of surgery with nondiabetic controls. Review of patient records revealed no significant difference in hospital stay or severity of operative and pathologic findings. However, diabetics suffered significantly more morbidity (38.9%) than nondiabetics (20.8%). Moreover, diabetic infection-related complications occurred at a rate nearly three times that of controls (19.4% vs 6.9%). The only mortalities were experienced by diabetics (4.2%) and were the direct result of the effects of sepsis. These findings suggest that acute cholecystitis in diabetics is associated with a higher incidence of infection-related complications and supports the need for expeditious operative therapy in symptomatic patients.
糖尿病对急性胆囊炎手术治疗相关风险的影响尚未明确界定。因此，开展了一项针对72例因急性胆囊炎需要紧急手术的糖尿病患者的病例对照研究。患者在年龄、性别和手术日期方面与非糖尿病对照组进行匹配。对患者记录的回顾显示，住院时间、手术及病理检查结果的严重程度均无显著差异。然而，糖尿病患者的发病率（38.9%）明显高于非糖尿病患者（20.8%）。此外，糖尿病患者感染相关并发症的发生率几乎是非糖尿病患者的三倍（19.4%对6.9%）。仅糖尿病患者出现了死亡（4.2%），且均为败血症所致的直接后果。这些发现表明，糖尿病患者的急性胆囊炎与感染相关并发症的发生率较高有关，并支持对有症状患者进行快速手术治疗的必要性。
