Erİk İshak, KiliÇ Gözde, ÖztÜrk Elif, KaraoĞlu Şengül Alpay, Yayli Nurettin
Department of Pharmacognosy, Faculty of Pharmacy, Karadeniz Technical University, Trabzon Turkey.
Institute of Health Sciences, Karadeniz Technical University, Trabzon Turkey.
Turk J Chem. 2020 Dec 16;44(6):1655-1662. doi: 10.3906/kim-2005-51. eCollection 2020.
The volatile components of essential oil (EO), SPME, and SPME of solvent extracts ( -hexane, methanol, and water) obtained from fresh subsp. ( ) were analyzed by GC-FID/MS. EO of gave 11 compounds in the percentage of 99.97%; capronaldehyde (37.01%), 2-( )-hexenal (23.19%), and -nonanal (19.05%) were found to be major constituents. SPME GC-FID/MS analyses of fresh plant and solvent extracts of revealed 7, 12, 7, and 4 compounds within the range of 99.7% to 99.9%. Limonene (76.5%, 41.7%, and 61.3%) was the major compound in SPMEs of the -hexane and methanol extracts. -Methoxy- -cresol (52.9%) was the main component in its water extract. The antimicrobial activity of EO and the solvent extracts of were screened against 9microorganisms. EO showed the best activity against , with 79.5 µg/mL MIC value. The -hexane, methanol, and water extracts were the most active against the within the range of 81.25-125.0 µg/mL (MIC). IC values for the lipase enzyme inhibitory activity of EO and solvent extracts ( -hexane, methanol, and water) were determined to be 59.87 µg/mL, 64.03 µg/mL, 101.91 µg/mL, and 121.24 µg/mL, respectively.
采用气相色谱 - 火焰离子化检测器/质谱联用（GC - FID/MS）对新鲜的[具体植物亚种名称]（[具体植物名称]）亚种中获得的精油（EO）、固相微萃取（SPME）以及溶剂提取物（正己烷、甲醇和水）的挥发性成分进行了分析。[具体植物名称]亚种的EO中有11种化合物，含量占99.97%；己醛（37.01%）、2 -（[具体结构]）-己烯醛（23.19%）和壬醛（19.05%）被发现是主要成分。对新鲜植物和[具体植物名称]亚种的溶剂提取物进行的SPME GC - FID/MS分析显示，在99.7%至99.9%的范围内分别有7种、12种、7种和4种化合物。柠檬烯（76.5%、41.7%和61.3%）是正己烷和甲醇提取物的SPME中的主要化合物。4 - 甲氧基 - 2 - 甲酚（52.9%）是其水提取物中的主要成分。对[具体植物名称]亚种的EO和溶剂提取物针对9种微生物进行了抗菌活性筛选。EO对[具体微生物名称]表现出最佳活性，最低抑菌浓度（MIC）值为79.5 μg/mL。正己烷、甲醇和水提取物对[具体微生物名称]的活性最强，MIC在81.25 - 125.0 μg/mL范围内。测定了EO和溶剂提取物（正己烷、甲醇和水）对脂肪酶的抑制活性的半数抑制浓度（IC）值，分别为59.87 μg/mL、64.03 μg/mL、101.91 μg/mL和121.24 μg/mL。
