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超声和CT在[病因未提及]所致原发性胸骨骨髓炎早期诊断及外科治疗中的作用:病例报告

Role of ultrasound and CT in the early diagnosis and surgical treatment of primary sternal osteomyelitis caused by Case reports.

作者信息

Qian Mengjiao, Wang Jing, Li Jun, Wang Sibo, Wang Zhongyin, Chen Xiao, Ou Haibo, Liang Yuanzhong, Peng Xuguan

机构信息

Department of Cardiothoracic Surgery, The First People's Hospital of Honghe Prefecture, Mengzi, Yunnan 661100, P.R. China.

Department of Radiology, The First People's Hospital of Honghe Prefecture, Mengzi, Yunnan 661100, P.R. China.

出版信息

Exp Ther Med. 2021 Mar;21(3):189. doi: 10.3892/etm.2021.9620. Epub 2021 Jan 7.

Abstract

Primary sternal osteomyelitis (PSO) caused by is a rare condition and most commonly associated with sickle cell disease. Only one such case has been previously reported in an infant (age, <1 year) worldwide. The present study reported on two infantile cases of PSO caused by in the absence of any hematological diseases. A total of two male infants (age, ≤1 year) were referred to our hospital for fever and rapid breathing accompanied by a chest wall mass involving the lower end of the sternum. Imaging findings on CT and ultrasound, which included sternal segment dislocation, lytic destruction and periosteal elevation, confirmed the diagnosis of PSO. Blood and purulent material cultures confirmed that the causative pathogen was . The infants were completely cured by sequential intravenous and oral antibiotics followed by surgical debridement. The infants remained symptom-free and local recurrence of PSO was not detected at follow-up. PSO caused by in the absence of any hematological diseases is a rare condition. Unfamiliarity with this disease may lead to a delay in diagnosis and serious complications. The current case report presents two cases of PSO along with a brief overview of the characteristics and management modalities for this condition, and it provides a comprehensive reference for pediatricians regarding this rare disease, particularly in infants.

摘要

由[病原体名称未给出]引起的原发性胸骨骨髓炎(PSO)是一种罕见疾病,最常与镰状细胞病相关。此前全球仅报道过1例婴儿(年龄<1岁)患此病的病例。本研究报告了2例在无任何血液系统疾病情况下由[病原体名称未给出]引起的婴儿PSO病例。共有2名男婴(年龄≤1岁)因发热、呼吸急促并伴有累及胸骨下端的胸壁肿块被转诊至我院。CT和超声检查结果显示胸骨节段脱位、溶骨性破坏和骨膜抬高,确诊为PSO。血液和脓性物质培养证实病原体为[病原体名称未给出]。通过序贯静脉及口服抗生素治疗,随后进行手术清创,婴儿完全治愈。随访期间婴儿无症状,未检测到PSO局部复发。在无任何血液系统疾病情况下由[病原体名称未给出]引起的PSO是一种罕见疾病。对此病不熟悉可能导致诊断延误及严重并发症。本病例报告展示了2例PSO病例,并简要概述了该病的特点及治疗方式,为儿科医生了解这种罕见疾病,尤其是婴儿期的该疾病,提供了全面的参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42fe/7812590/83270b618d5f/etm-21-03-09620-g00.jpg

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