Mehta Vishal, Kumar Ritesh, Prabhakar Rathod, Sharma Chandra B, Thomas Aneesha
Department of General Medicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Department of Neurology, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
J Family Med Prim Care. 2022 Jan;11(1):386-389. doi: 10.4103/jfmpc.jfmpc_1652_21. Epub 2022 Jan 31.
Neurotoxic snakebites are a common emergency in tropical countries and account for significant morbidity and mortality worldwide. Manifestations vary from mild ptosis and ophthalmoplegia to severe flaccid paralysis with ventilatory failure. At times, the neuromuscular paralysis may be severe enough for patients to be misdiagnosed as a locked-in syndrome or brain dead. Occult snakebites, wherein patients are unaware of the bite and fang marks are absent, have been reported in kraits, an endemic neurotoxic snake belonging to the Elapidae family. We report a series of three cases in which young males presented with dramatic neuromuscular paralysis and were likely suffering from elapid snake bites. Each of these patients presented an intriguing clinical challenge and had different in-hospital outcomes. Primary care physicians in the emergency department are usually the first respondents to such patients. Owing to a lack of snake bite history and unavailability of specific diagnostic tests, severe envenomation presents a challenge for physicians, unless they are aware of it and a high level of suspicion is maintained.
神经毒性蛇咬伤在热带国家是常见的急症,在全球范围内导致显著的发病率和死亡率。其表现从轻度上睑下垂和眼肌麻痹到伴有呼吸衰竭的严重弛缓性麻痹不等。有时,神经肌肉麻痹可能严重到足以使患者被误诊为闭锁综合征或脑死亡。隐匿性蛇咬伤已有报道,即患者未意识到被咬伤且无牙痕,在眼镜蛇科的一种地方性神经毒性蛇——金环蛇中出现过。我们报告了一系列三例年轻男性患者,他们表现出严重的神经肌肉麻痹,很可能是被眼镜蛇科蛇咬伤。这些患者中的每一位都带来了一个有趣的临床挑战,且在医院的结局各不相同。急诊科的初级保健医生通常是这类患者的首批接诊人员。由于缺乏蛇咬伤史且没有特定的诊断测试,除非医生意识到并保持高度怀疑,否则严重的蛇毒中毒会给医生带来挑战。