糖皮质激素单药治疗他汀类药物诱导的坏死性自身免疫性肌病
Treatment of Statin-Induced Necrotizing Autoimmune Myopathy With Glucocorticoid Monotherapy.
作者信息
Lempel Matthew, Molla Ermal
机构信息
Internal Medicine, Waterbury Hospital, Waterbury, USA.
Rheumatology, Waterbury Hospital, Waterbury, USA.
出版信息
Cureus. 2020 Dec 14;12(12):e12086. doi: 10.7759/cureus.12086.
Statins are widely prescribed medications to prevent cardiovascular events such as myocardial infarction and stroke. Both myalgia and myopathy are well-known potential side effects of statins. However, a rare and severe form of statin-induced necrotizing autoimmune myopathy (SINAM) has recently been described and can lead to debilitating weakness, often requiring immunosuppressive therapy. We report a case of a 73-year-old male who made a complete recovery from SINAM following a three-month course of prednisone monotherapy.
他汀类药物是广泛用于预防心血管事件（如心肌梗死和中风）的处方药。肌痛和肌病都是众所周知的他汀类药物潜在副作用。然而，最近描述了一种罕见且严重的他汀类药物诱导的坏死性自身免疫性肌病（SINAM），它可导致使人衰弱的肌无力，通常需要免疫抑制治疗。我们报告了一例73岁男性患者，在接受三个月的泼尼松单药治疗后，从SINAM中完全康复。
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