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复发性坏死性筋膜炎:1例糖尿病患者暴发性和亚急性坏死性筋膜炎的病例报告

Recurrent Necrotizing Fasciitis: A Case Report of Fulminant and Sub-Acute Necrotizing Fasciitis in a Diabetic Patient.

作者信息

Peters Johannes, Iacobelli Jean, Ryan Emily

机构信息

General Surgery, Royal Perth Hospital, Perth, AUS.

Pathology, Fiona Stanley Hospital, Perth, AUS.

出版信息

Cureus. 2020 Dec 18;12(12):e12153. doi: 10.7759/cureus.12153.

DOI:10.7759/cureus.12153
PMID:33489565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7813526/
Abstract

Necrotizing fasciitis is an uncommon and deadly disease entity characterized by rapidly progressing skin and soft tissue destruction. It presents on a spectrum from an initially indolent appearing sub-acute form to a hyperacute fulminant course. It may often be misdiagnosed due to the paucity of signs early in the disease course and as it can initially mimic other less serious soft tissue infections. Necrotizing soft tissue infections have both high morbidity and mortality. We present a case of a 72-year-old male patient with two anatomically and temporally separate necrotizing infections. The first necrotizing infection was diagnosed after an extended time, due to the subacute disease course in the setting of an abdominal wall infection. The second presentation was a hyperacute fulminant course in the setting of a necrotizing infection of the scrotum. In both instances, once identified, appropriate management was followed: resuscitation, broad-spectrum antibiotics, and most importantly radical surgical debridement. Extensive multidisciplinary inpatient and outpatient input was required to aid the patient's recovery. The presented case demonstrates the necrotizing soft tissue infection's spectrum of disease and the diagnostic dilemma it presents to family physicians and emergency departments alike. The only definitive management step is immediate and radical resection of the affected tissue. Extensive debridement and the resultant tissue defect require comprehensive multidisciplinary care during the extended rehabilitation and wound care treatment plan. Rapid recognition, urgent surgical debridement, and specialist care are required to reduce the mortality and morbidity associated with necrotizing soft tissue infections.

摘要

坏死性筋膜炎是一种罕见且致命的疾病,其特征为皮肤和软组织迅速进行性破坏。它呈现出从最初看似隐匿的亚急性形式到超急性暴发性病程的一系列表现。由于疾病早期体征较少,且最初可能类似其他不太严重的软组织感染,它常常可能被误诊。坏死性软组织感染具有高发病率和高死亡率。我们报告一例72岁男性患者,患有两处解剖学和时间上分离的坏死性感染。第一次坏死性感染在较长时间后才被诊断出来,因为腹壁感染情况下病程呈亚急性。第二次表现为阴囊坏死性感染情况下的超急性暴发性病程。在这两种情况下,一旦确诊,均采取了适当的治疗措施:复苏、广谱抗生素治疗,最重要的是进行根治性手术清创。需要广泛的多学科住院和门诊投入以帮助患者康复。所报告的病例展示了坏死性软组织感染的疾病谱以及它给家庭医生和急诊科带来的诊断困境。唯一确定的治疗步骤是立即对受影响组织进行根治性切除。在延长的康复和伤口护理治疗计划期间,广泛的清创和由此产生的组织缺损需要全面的多学科护理。需要快速识别、紧急手术清创和专科护理,以降低与坏死性软组织感染相关的死亡率和发病率。

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本文引用的文献

1
Mortality Risk in Necrotizing Fasciitis: National Prevalence, Trend, and Burden.坏死性筋膜炎的死亡率:全国流行率、趋势和负担。
Surg Infect (Larchmt). 2020 Dec;21(10):840-852. doi: 10.1089/sur.2019.277. Epub 2020 Mar 20.
2
[Necrotizing fasciitis of the extremities and trunk].[四肢及躯干坏死性筋膜炎]
Chirurg. 2020 Apr;91(4):301-306. doi: 10.1007/s00104-019-01082-w.
3
Fournier Gangrene: A Review for Emergency Clinicians.福尼尔坏疽:急诊临床医生综述
坏死性软组织感染:一项关于治疗与结局的单中心回顾性研究
Cureus. 2021 May 15;13(5):e15039. doi: 10.7759/cureus.15039.
J Emerg Med. 2019 Oct;57(4):488-500. doi: 10.1016/j.jemermed.2019.06.023. Epub 2019 Aug 28.
4
Necrotizing Fasciitis: An Overview and 2 Illustrative Cases.坏死性筋膜炎:概述及2例说明性病例
Int J Low Extrem Wounds. 2018 Dec;17(4):295-300. doi: 10.1177/1534734618804037. Epub 2018 Nov 13.
5
Fournier's Gangrene: Literature Review and Clinical Cases.福尼尔坏疽:文献综述与临床病例
Urol Int. 2018;101(1):91-97. doi: 10.1159/000490108. Epub 2018 Jun 27.
6
Evaluation and Management of Necrotizing Soft Tissue Infections.坏死性软组织感染的评估与管理
Infect Dis Clin North Am. 2017 Sep;31(3):497-511. doi: 10.1016/j.idc.2017.05.011.
7
A case report of necrotizing fasciitis of the abdominal wall: A rare, life-threatening complication of a common disease process.腹壁坏死性筋膜炎病例报告:一种常见疾病过程中罕见的、危及生命的并发症。
Int J Surg Case Rep. 2016;28:355-356. doi: 10.1016/j.ijscr.2016.09.005. Epub 2016 Sep 28.
8
[Necrotizing fasciitis - a clinical diagnosis].[坏死性筋膜炎——一种临床诊断]
Orthopade. 2016 Dec;45(12):1072-1079. doi: 10.1007/s00132-016-3318-x.
9
Fournier's Gangrene: Epidemiology and Outcomes in the General US Population.福尼尔坏疽:美国普通人群中的流行病学及预后情况
Urol Int. 2016;97(3):249-259. doi: 10.1159/000445695. Epub 2016 May 14.
10
Fournier's gangrene--current concepts.福尼尔坏疽——当前概念
Pol J Microbiol. 2014;63(3):267-73.