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复发性坏死性筋膜炎:1例糖尿病患者暴发性和亚急性坏死性筋膜炎的病例报告

Recurrent Necrotizing Fasciitis: A Case Report of Fulminant and Sub-Acute Necrotizing Fasciitis in a Diabetic Patient.

作者信息

Peters Johannes, Iacobelli Jean, Ryan Emily

机构信息

General Surgery, Royal Perth Hospital, Perth, AUS.

Pathology, Fiona Stanley Hospital, Perth, AUS.

出版信息

Cureus. 2020 Dec 18;12(12):e12153. doi: 10.7759/cureus.12153.

Abstract

Necrotizing fasciitis is an uncommon and deadly disease entity characterized by rapidly progressing skin and soft tissue destruction. It presents on a spectrum from an initially indolent appearing sub-acute form to a hyperacute fulminant course. It may often be misdiagnosed due to the paucity of signs early in the disease course and as it can initially mimic other less serious soft tissue infections. Necrotizing soft tissue infections have both high morbidity and mortality. We present a case of a 72-year-old male patient with two anatomically and temporally separate necrotizing infections. The first necrotizing infection was diagnosed after an extended time, due to the subacute disease course in the setting of an abdominal wall infection. The second presentation was a hyperacute fulminant course in the setting of a necrotizing infection of the scrotum. In both instances, once identified, appropriate management was followed: resuscitation, broad-spectrum antibiotics, and most importantly radical surgical debridement. Extensive multidisciplinary inpatient and outpatient input was required to aid the patient's recovery. The presented case demonstrates the necrotizing soft tissue infection's spectrum of disease and the diagnostic dilemma it presents to family physicians and emergency departments alike. The only definitive management step is immediate and radical resection of the affected tissue. Extensive debridement and the resultant tissue defect require comprehensive multidisciplinary care during the extended rehabilitation and wound care treatment plan. Rapid recognition, urgent surgical debridement, and specialist care are required to reduce the mortality and morbidity associated with necrotizing soft tissue infections.

摘要

坏死性筋膜炎是一种罕见且致命的疾病,其特征为皮肤和软组织迅速进行性破坏。它呈现出从最初看似隐匿的亚急性形式到超急性暴发性病程的一系列表现。由于疾病早期体征较少,且最初可能类似其他不太严重的软组织感染,它常常可能被误诊。坏死性软组织感染具有高发病率和高死亡率。我们报告一例72岁男性患者,患有两处解剖学和时间上分离的坏死性感染。第一次坏死性感染在较长时间后才被诊断出来,因为腹壁感染情况下病程呈亚急性。第二次表现为阴囊坏死性感染情况下的超急性暴发性病程。在这两种情况下,一旦确诊,均采取了适当的治疗措施:复苏、广谱抗生素治疗,最重要的是进行根治性手术清创。需要广泛的多学科住院和门诊投入以帮助患者康复。所报告的病例展示了坏死性软组织感染的疾病谱以及它给家庭医生和急诊科带来的诊断困境。唯一确定的治疗步骤是立即对受影响组织进行根治性切除。在延长的康复和伤口护理治疗计划期间,广泛的清创和由此产生的组织缺损需要全面的多学科护理。需要快速识别、紧急手术清创和专科护理,以降低与坏死性软组织感染相关的死亡率和发病率。

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