Alagawany Mahmoud, Attia Youssef A, Farag Mayada R, Elnesr Shaaban S, Nagadi Sameer A, Shafi Manal E, Khafaga Asmaa F, Ohran Husein, Alaqil Abdulaziz A, Abd El-Hack Mohamed E
Department of Poultry, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.
Agriculture Department, Faculty of Environmental Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Front Vet Sci. 2021 Jan 8;7:570748. doi: 10.3389/fvets.2020.570748. eCollection 2020.
The novel coronavirus (SARS-CoV-2) infection (COVID-19) has raised considerable concern on the entire planet. On March 11, 2020, COVID-19 was categorized by the World Health Organization (WHO) as a pandemic infection, and by March 18, 2020, it has spread to 146 countries. The first internal defense line against numerous diseases is personalized immunity. Although it cannot be claimed that personalized nutrition will have an immediate impact on a global pandemic, as the nutritional interventions required a long time to induce beneficial outcomes on immunity development, nutritional strategies are still able to clarify and have a beneficial influence on the interplay between physiology and diet, which could make a positive contribution to the condition in the next period. As such, a specific goal for every practitioner is to evaluate different tests to perceive the status of the patient, such as markers of inflammation, insulin regulation, and nutrient status, and to detect possible imbalances or deficiencies. During the process of disease development, the supplementation and addition of different nutrients and nutraceuticals can influence not only the viral replication but also the cellular mechanisms. It is essential to understand that every patient has its individual needs. Even though many nutrients, nutraceuticals, and drugs have beneficial effects on the immune response and can prevent or ameliorate viral infections, it is essential to detect at what stage in COVID-19 progression the patient is at the moment and decide what kind of nutrition intervention is necessary. Furthermore, understanding the pathogenesis of coronavirus infection is critical to make proper recommendations.
新型冠状病毒（SARS-CoV-2）感染（COVID-19）已引起全球的广泛关注。2020年3月11日，世界卫生组织（WHO）将COVID-19归类为大流行性感染，到2020年3月18日，它已传播到146个国家。抵御众多疾病的第一道内部防线是个性化免疫。尽管不能断言个性化营养会对全球大流行产生立竿见影的影响，因为营养干预需要很长时间才能对免疫发育产生有益效果，但营养策略仍能够阐明并对生理与饮食之间的相互作用产生有益影响，这可能在下一阶段对病情产生积极作用。因此，每位从业者的一个具体目标是评估不同的检测方法，以了解患者的状况，例如炎症标志物、胰岛素调节和营养状况，并检测可能存在的失衡或缺乏情况。在疾病发展过程中，补充和添加不同的营养素及营养保健品不仅会影响病毒复制，还会影响细胞机制。必须明白每个患者都有其个体需求。尽管许多营养素、营养保健品和药物对免疫反应有有益影响，并且可以预防或改善病毒感染，但至关重要的是要确定患者目前处于COVID-19病程的哪个阶段，并决定需要何种营养干预措施。此外，了解冠状病毒感染的发病机制对于做出适当的建议至关重要。
