Saha Biplab K, Ghalib Sana, Chieng Hau, Pezzano Chad, Lydon Darren, Feustel Paul, Smith Thomas C, Chopra Amit
Department of Pulmonary and Critical Care Medicine, Ozarks Medical Center, West Plains, MO.
Department of Pulmonary and Critical Care Medicine, Albany Medical Center, Albany, NY.
Crit Care Explor. 2021 Jan 13;3(1):e0328. doi: 10.1097/CCE.0000000000000328. eCollection 2021 Jan.
Acute respiratory distress syndrome secondary to severe acute respiratory syndrome coronavirus-2 pneumonia or coronavirus disease 2019-related acute respiratory distress syndrome is the primary cause of mortality in coronavirus disease 2019. Some studies have described the concept of "high and low" elastance coronavirus disease 2019-related acute respiratory distress syndrome and proposed individualized management for the acute respiratory distress syndrome, deviating from low tidal volume ventilation. We report simultaneously measured respiratory parameters (static lung compliance, alveolar dead space ventilation, and shunt fraction) in 14 patients with advanced coronavirus disease 2019-related acute respiratory distress syndrome. The results were consistent with typical acute respiratory distress syndrome and did not support the concept of high-type coronavirus disease 2019-related acute respiratory distress syndrome and low-type coronavirus disease 2019-related acute respiratory distress syndrome.
严重急性呼吸综合征冠状病毒2型肺炎继发的急性呼吸窘迫综合征或2019冠状病毒病相关的急性呼吸窘迫综合征是2019冠状病毒病死亡的主要原因。一些研究描述了“高弹性”和“低弹性”2019冠状病毒病相关急性呼吸窘迫综合征的概念，并提出了针对急性呼吸窘迫综合征的个体化管理，偏离了低潮气量通气。我们报告了14例晚期2019冠状病毒病相关急性呼吸窘迫综合征患者同时测量的呼吸参数（静态肺顺应性、肺泡死腔通气和分流分数）。结果与典型急性呼吸窘迫综合征一致，不支持“高弹性型”和“低弹性型”2019冠状病毒病相关急性呼吸窘迫综合征的概念。
