Swiss Center for Affective Sciences, University of Geneva, Switzerland.
Laboratory for the Study of Emotion Elicitation and Expression (E3Lab), Department of Psychology, University of Geneva, Switzerland.
Ann Behav Med. 2021 Aug 23;55(9):904-917. doi: 10.1093/abm/kaaa120.
Despite the key role of physical activity in the management of diabetes, many individuals with diabetes do not engage in the recommended levels of physical activity. However, our knowledge of the mechanisms underlying the relationship between diabetes and physical inactivity is limited.
To investigate the associations between diabetes and the levels and evolution of physical activity across aging, and to determine whether physical, emotional, and cognitive factors mediate these associations.
Data from 105,622 adults aged 50-96 years from the Survey of Health, Ageing and Retirement in Europe (SHARE) were used in adjusted linear mixed models to examine whether diabetes was associated with physical activity levels and variations across aging. The potential mediators were subjective energy, muscle strength, physical and cognitive disability, sleep problems, depressive symptoms, and cognitive functions. The variables were measured up to seven times over a 13-year period.
Individuals with diabetes demonstrated a lower level and a steeper decrease in physical activity across aging than individual without diabetes. Mediators explained ~53% and 94% of the association of diabetes with the level of physical activity and with the linear evolution of physical activity across aging, respectively. All mediators were significantly associated with physical activity. Physical and cognitive disability as well as depressive symptoms were the strongest mediators, while sleep was the lowest one.
These findings suggest that the etiology of physical inactivity in individuals with diabetes can result from several physical, emotional, and cognitive changes associated with the emergence of this disease.
尽管身体活动在糖尿病管理中起着关键作用，但许多糖尿病患者并未达到推荐的身体活动水平。然而，我们对糖尿病与身体不活动之间关系的潜在机制知之甚少。
研究糖尿病与身体活动水平及其在衰老过程中的变化之间的关联，并确定身体、情绪和认知因素是否在这些关联中起中介作用。
利用来自欧洲健康、衰老和退休调查（SHARE）的 105622 名 50-96 岁成年人的数据，采用调整后的线性混合模型，检验糖尿病是否与身体活动水平以及随年龄的变化有关。潜在的中介因素包括主观能量、肌肉力量、身体和认知障碍、睡眠问题、抑郁症状和认知功能。这些变量在 13 年期间被测量了多达 7 次。
与无糖尿病者相比，糖尿病患者的身体活动水平较低，且随年龄增长呈更陡峭的下降趋势。中介因素分别解释了糖尿病与身体活动水平相关的 53%和与身体活动随年龄线性变化相关的 94%的关联。所有的中介因素都与身体活动显著相关。身体和认知障碍以及抑郁症状是最强的中介因素，而睡眠是最弱的中介因素。
这些发现表明，糖尿病患者身体不活动的病因可能是由于与该疾病出现相关的几种身体、情绪和认知变化所致。
