Department of Chemistry, Kyungpook National University, Daegu, Korea.
Oil and POPs Research Group, Korea Institute of Ocean Science and Technology, Geoje, Korea.
Mass Spectrom Rev. 2022 Mar;41(2):352-369. doi: 10.1002/mas.21684. Epub 2021 Jan 24.
Owing to the increasing environmental and climate changes globally, there is an increasing interest in the molecular-level understanding of environmental organic compound mixtures, that is, the pursuit of complete and detailed knowledge of the chemical compositions and related chemical reactions. Environmental organic molecule mixtures, including those in air, soil, rivers, and oceans, have extremely complex and heterogeneous chemical compositions. For their analyses, ultrahigh-resolution and sub-ppb level mass accuracy, achievable using Fourier-transform ion cyclotron resonance mass spectrometry (FT-ICR MS), are important. FT-ICR MS has been successfully used to analyze complex environmental organic molecule mixtures such as natural, soil, particulate, and dissolved organic matter. Despite its success, many limitations still need to be overcome. Sample preparation, ionization, structural identification, chromatographic separation, and data interpretation are some key areas that have been the focus of numerous studies. This review describes key developments in analytical techniques in these areas to aid researchers seeking to start or continue investigations for the molecular-level understanding of environmental organic compound mixtures.
由于全球环境和气候变化的不断增加，人们对环境中有机化合物混合物的分子水平理解越来越感兴趣，即追求对化学成分和相关化学反应的全面和详细了解。环境有机分子混合物，包括空气中、土壤中、河流中和海洋中的有机分子混合物，具有极其复杂和不均匀的化学成分。为了对其进行分析，傅里叶变换离子回旋共振质谱（FT-ICR MS）可实现超高分辨率和亚 ppb 级质量精度，这一点非常重要。FT-ICR MS 已成功用于分析复杂的环境有机分子混合物，如天然、土壤、颗粒和溶解有机物。尽管取得了成功，但仍有许多局限性需要克服。样品制备、离子化、结构鉴定、色谱分离和数据解释是一些关键领域，这些领域一直是众多研究的重点。本综述描述了这些领域分析技术的关键进展，以帮助那些希望开始或继续进行环境有机化合物混合物分子水平理解研究的研究人员。
