Romanova L K, Serebriakov I S, Lebedev D B, Iarygin V N
Biull Eksp Biol Med. 1988 Feb;105(2):231-5.
Partial "sympathectomy" in the neonatal BALB mice was achieved by the treatment with guanethidine. The number of neurons in the stellate ganglion decreased to 20% of the control values and remained constant throughout the subsequent period of 1 month. Partial "chemical sympathectomy" did not affect the postnatal growth and development of the lungs. Partial "chemical sympathectomy" significantly increased the number of secreting cells in bronchiolar and alveolar regions. Secretory activity of the alveolocyte population, type two, synthetizing and secreting surfactant also increased. It has been concluded that the partial "chemical sympathectomy" stimulated the alveolar surfactant secretion.
通过给予胍乙啶对新生BALB小鼠进行部分“交感神经切除术”。星状神经节中的神经元数量减少至对照值的20%，并在随后的1个月内保持恒定。部分“化学性交感神经切除术”不影响肺的出生后生长和发育。部分“化学性交感神经切除术”显著增加了细支气管和肺泡区域分泌细胞的数量。合成并分泌表面活性剂的Ⅱ型肺泡上皮细胞群体的分泌活性也增加。得出的结论是，部分“化学性交感神经切除术”刺激了肺泡表面活性物质的分泌。
