Richards M A, Webb J A, Jewell S E, Gregory W M, Reznek R H
ICRF Department of Medical Oncology, St. Bartholomew's Hospital, London.
Br J Radiol. 1988 Jan;61(721):30-3. doi: 10.1259/0007-1285-61-721-30.
Magnetic resonance images of the spine, sternum, femoral heads and upper femoral shafts were obtained from 90 healthy volunteers to determine the normal ranges of spin lattice relaxation time (T1) for different regions of the bone marrow. The influence of age, sex and oral contraceptive usage on bone marrow T1 was assessed. Differences observed between the T1 of the various regions of the bone marrow examined were consistent with the expected distribution of erythropoietic cells and fatty marrow. Bone marrow T1 was found to decrease with age, significantly lower mean T1 values being observed in subjects over 40 years of age than for those in the 20-40 years age group. The mean bone marrow T1 of females in the 20-40 years age group was significantly higher than that for males of comparable age. For subjects over 40 years of age, the difference in bone marrow T1 observed between males and females was not significant. Oral contraceptive usage had no effect on bone marrow T1.
从90名健康志愿者身上获取了脊柱、胸骨、股骨头和股骨干上段的磁共振图像，以确定不同骨髓区域的自旋晶格弛豫时间（T1）的正常范围。评估了年龄、性别和口服避孕药的使用对骨髓T1的影响。在所检查的骨髓各个区域的T1之间观察到的差异与红系造血细胞和脂肪骨髓的预期分布一致。发现骨髓T1随年龄增长而降低，40岁以上受试者的平均T1值明显低于20至40岁年龄组的受试者。20至40岁年龄组女性的平均骨髓T1明显高于同龄男性。对于40岁以上的受试者，男性和女性之间观察到的骨髓T1差异不显著。口服避孕药的使用对骨髓T1没有影响。
