Richards M A, Webb J A, Jewell S E, Gregory W M, Reznek R H
ICRF Department of Medical Oncology, St Bartholomew's Hospital, London.
Br J Radiol. 1988 Jan;61(721):34-7. doi: 10.1259/0007-1285-61-721-34.
Magnetic resonance imaging of 81 healthy adult volunteers has been undertaken to establish the normal range of liver spin lattice relaxation time (T1) at 0.08 tesla. The influence of age, sex and oral contraceptive usage has been assessed. Liver T1 decreased with age. The mean liver T1 of subjects under 40 years of age was significantly longer than that of older subjects. A wider range of T1 values was observed in the younger age group. No difference in T1 was found between males and females who were not oral contraceptive users. The mean liver T1 of females who were taking the pill was significantly longer than that of females of similar age who were not oral contraceptive users. Serial examinations of eight oral contraceptive users showed that mean liver T1 values were significantly longer in the 3 weeks during which they were taking the pill than during the week off the pill.
对81名健康成年志愿者进行了磁共振成像，以确定0.08特斯拉时肝脏自旋晶格弛豫时间（T1）的正常范围。评估了年龄、性别和口服避孕药使用情况的影响。肝脏T1随年龄增长而降低。40岁以下受试者的平均肝脏T1明显长于年龄较大的受试者。在较年轻年龄组中观察到更广泛的T1值范围。未使用口服避孕药的男性和女性之间T1无差异。服用避孕药的女性的平均肝脏T1明显长于年龄相仿但未使用口服避孕药的女性。对8名口服避孕药使用者的系列检查表明，她们服药的3周内平均肝脏T1值明显长于停药的那一周。
