Department of Food Chemistry and Nutrition, Medical College, Jagiellonian University, Medyczna 9, 30-688, Kraków, Poland.
Department of Pharmacognosy, Medical College, Jagiellonian University, 30-688, Kraków, Poland.
Plant Foods Hum Nutr. 2021 Mar;76(1):76-82. doi: 10.1007/s11130-020-00877-1. Epub 2021 Jan 25.
Kohlrabi sprouts are just gaining popularity as the new example of functional food. The study was focused on the influence of germination time and light conditions on glucosinolates, phenolic acids, flavonoids, and fatty acids content in kohlrabi sprouts, in comparison to the bulbs. The effect of kohlrabi products on SW480, HepG2 and BJ cells was also determined. The length of sprouting time and light availability significantly influenced the concentrations of the phenolic compounds. Significant differences in progoitrin concentrations were observed between the sprouts harvested in light and in the darkness, with significantly lower content for darkness conditions. Erucic acid was the dominant fatty acid found in sprouts (14.5-34.5%). Sprouts and bulbs were less toxic to normal than to cancer cells. The sprouts stimulated necrosis (56.4%) more than apoptosis (34.1%) in SW480 cells, while the latter effect was predominant for the bulbs. Both sprouts and bulbs caused rather necrosis (45.5 and 63.9%) than apoptosis (32 and 32.5%) in HepG2 cells.
椰菜芽菜作为新的功能性食品正在逐渐流行起来。本研究主要关注发芽时间和光照条件对椰菜芽菜和鳞茎中硫代葡萄糖苷、酚酸、类黄酮和脂肪酸含量的影响。还测定了椰菜芽菜产品对 SW480、HepG2 和 BJ 细胞的影响。发芽时间和光照条件的长短显著影响了酚类化合物的浓度。在光照和黑暗条件下收获的椰菜芽菜中发现了显著不同的前硫代葡萄糖苷浓度,黑暗条件下的含量明显较低。在芽菜中发现的主要脂肪酸是芥酸(14.5-34.5%)。芽菜和鳞茎对正常细胞的毒性小于对癌细胞的毒性。芽菜在 SW480 细胞中刺激坏死(56.4%)多于凋亡(34.1%),而在鳞茎中则以凋亡为主。芽菜和鳞茎在 HepG2 细胞中引起的坏死(45.5%和 63.9%)多于凋亡(32%和 32.5%)。