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胰胃吻合术:慢性胰腺炎疼痛缓解的首选手术。

Pancreaticogastrostomy: the preferred operation for pain relief in chronic pancreatitis.

作者信息

Pain J A, Knight M J

机构信息

Pancreaticobiliary Unit, St. George's Hospital, London, UK.

出版信息

Br J Surg. 1988 Mar;75(3):220-2. doi: 10.1002/bjs.1800750310.

Abstract

We present the results of surgery in 53 patients with intractable pain due to chronic pancreatitis associated with pancreatic duct dilatation. Using a limited mucosal to mucosal anastomosis over a silastic T tube the main pancreatic duct was drained in 33 patients into a Roux-en-Y jejunal loop (pancreaticojejunostomy, PJ) and in 20 patients into the stomach (pancreaticogastrostomy, PG). There was one postoperative death in the PJ group and none in the PG group. All patients were followed up for a minimum of four years. There was significantly greater pain relief in the PG group both at 1 (P less than 0.01) and 4 years (P less than 0.05) after surgery. We argue that PG is the operation of choice to relieve intractable pain in most patients with chronic pancreatitis associated with duct dilatation.

摘要

我们展示了53例因慢性胰腺炎伴胰管扩张而患有顽固性疼痛患者的手术结果。通过在硅胶T管上进行有限的黏膜对黏膜吻合术,33例患者的主胰管被引流至Roux-en-Y空肠袢(胰管空肠吻合术,PJ),20例患者的主胰管被引流至胃(胰管胃吻合术,PG)。PJ组有1例术后死亡,PG组无术后死亡。所有患者均接受了至少四年的随访。术后1年(P<0.01)和4年(P<0.05)时,PG组的疼痛缓解明显更显著。我们认为,对于大多数伴有胰管扩张的慢性胰腺炎患者,PG是缓解顽固性疼痛的首选手术方式。

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