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哌仑西平对胃溃疡愈合的影响。一项住院患者的双盲研究(作者译)

[Influence of pirenzepin on healing of gastric ulcer. A double blind study in in-patients (author's transl)].

作者信息

Schmid E, Blaich E

出版信息

Z Gastroenterol. 1978 Dec;16(12):778-80.

PMID:33495
Abstract

In a double-blind study the influence of Pirenzepin on ulcer healing was studied in 28 in-patients with gastric ulcer under endoscopic control. The ulcer size was reduced by Pirenzepin significantly quicker, and the number of ulcers healed after three weeks treatment with Pirenzepin was significantly higher than under placebo. As to accompanying symptoms appetite stimulation was significantly more frequent with Pirenzepin compared to placebo. No patient complained of dryness of the mouth.

摘要

在一项双盲研究中,在内镜控制下,对28例胃溃疡住院患者研究了哌仑西平对溃疡愈合的影响。哌仑西平能显著更快地减小溃疡大小,且用哌仑西平治疗三周后愈合的溃疡数量显著高于安慰剂组。至于伴随症状,与安慰剂相比,哌仑西平引起食欲增加的情况明显更常见。没有患者抱怨口干。

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