Oueslati Saoussen, Emeraud Cécile, Grosperrin Victor, Levy Marc, Cotellon Garance, Creton Elodie, Gauthier Lauraine, Bonnin Rémy A, Naas Thierry, Dortet Laurent
Faculty of Medicine, INSERM UMR 1184, RESIST Unit Paris-Saclay University, Le Kremlin-Bicêtre, France.
Bacteriology-Hygiene Unit, Assistance Publique/Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, France.
Antimicrob Agents Chemother. 2021 Mar 18;65(4). doi: 10.1128/AAC.02437-20.
The whole-genome sequencing analysis revealed a polyclonal dissemination of NDM-1 and NDM-9 variants in ( = 20) and ( = 2) in Tahiti since 2015 via interspecies transfer of three different -carrying plasmids (IncR, IncHI2, and IncF) and patient-to-patient cross-transmission. It highlights the potential risk of importation of NDM producers in France, where French Polynesia is not considered a foreign country from which repatriated patients have to be screened.
全基因组测序分析显示，自2015年以来，在塔希提岛，通过三种携带不同质粒（IncR、IncHI2和IncF）的种间转移以及患者之间的交叉传播，20例患者中出现了NDM-1和NDM-9变体的多克隆传播，另有2例患者出现了这种情况。这凸显了法国引入产NDM细菌的潜在风险，在法国，法属波利尼西亚不被视为外国，因此回国患者无需接受筛查。
