Lu Jian-Yu, Yu Yu-Sheng, Chen Tung-Bo, Chang Chiung-Fen, Tamulevičius Sigitas, Erts Donats, Wu Kevin C-W, Gu Yesong
Department of Chemical and Materials Engineering, Tunghai University, No.1727, Sec.4, Taiwan Boulevard, Xitun District, Taichung 40704, Taiwan.
Department of Chemical Engineering, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan.
Polymers (Basel). 2021 Jan 22;13(3):343. doi: 10.3390/polym13030343.
Hydroquinone (HQ) is one of the major deleterious metabolites of benzene in the human body, which has been implicated to cause various human diseases. In order to fabricate a feasible sensor for the accurate detection of HQ, we attempted to electrochemically modify a piece of common 2B pencil lead (PL) with the conductive poly(3,4-ethylenedioxythiophene) or PEDOT film to construct a PEDOT/PL electrode. We then examined the performance of PEDOT/PL in the detection of hydroquinone with different voltammetry methods. Our results have demonstrated that PEDOT film was able to dramatically enhance the electrochemical response of pencil lead electrode to hydroquinone and exhibited a good linear correlation between anodic peak current and the concentration of hydroquinone by either cyclic voltammetry or linear sweep voltammetry. The influences of PEDOT film thickness, sample pH, voltammetry scan rate, and possible chemical interferences on the measurement of hydroquinone have been discussed. The PEDOT film was further characterized by SEM with EDS and FTIR spectrum, as well as for stability with multiple measurements. Our results have demonstrated that the PEDOT modified PL electrode could be an attractive option to easily fabricate an economical sensor and provide an accurate and stable approach to monitoring various chemicals and biomolecules.
对苯二酚（HQ）是人体中苯的主要有害代谢产物之一，与多种人类疾病的发生有关。为了制造一种可行的传感器以准确检测HQ，我们尝试用导电聚（3,4-乙撑二氧噻吩）或聚3,4-乙撑二氧噻吩（PEDOT）膜对一根普通的2B铅笔芯（PL）进行电化学修饰，以构建一个PEDOT/PL电极。然后，我们用不同的伏安法研究了PEDOT/PL在检测对苯二酚方面的性能。我们的结果表明，PEDOT膜能够显著增强铅笔芯电极对对苯二酚的电化学响应，并且通过循环伏安法或线性扫描伏安法，阳极峰值电流与对苯二酚浓度之间呈现出良好的线性相关性。讨论了PEDOT膜厚度、样品pH值、伏安扫描速率以及可能的化学干扰对对苯二酚测量的影响。通过扫描电子显微镜（SEM）结合能谱仪（EDS）和傅里叶变换红外光谱（FTIR）对PEDOT膜进行了进一步表征，并对其多次测量的稳定性进行了研究。我们的结果表明，PEDOT修饰的PL电极可能是一种有吸引力的选择，能够轻松制造出一种经济的传感器，并提供一种准确且稳定的方法来监测各种化学物质和生物分子。
