Rajendran Jerome
Department of Chemistry, SRM Institute of Science and Technology, Kattankulathur 603203, Tamil Nadu, India.
J Hazard Mater. 2023 May 5;449:130979. doi: 10.1016/j.jhazmat.2023.130979. Epub 2023 Feb 11.
Thiocyanate (SCN) is a hazardous byproduct of the detoxification of cyanide. Even in minute quantity, the SCN has a negative impact on health. Although there are several ways for SCN analysis, an efficient electrochemical procedure has hardly ever been attempted. Here, the author reports the development of a highly selective and sensitive electrochemical sensor for SCN utilizing Poly (3, 4-Ethylenedioxythiophene) incorporated MXene (PEDOT/MXene) modified screen-printed electrode (SPE). The Raman, X-ray photoelectron (XPS), and X-ray diffraction (XRD) analyses support the effective integration of PEDOT on the MXene surface. Further, scanning electron microscopy (SEM) is employed to demonstrate the formation of MXene and PEDOT/MXene hybrid film. In order to specifically detect SCN in phosphate buffer media (pH 7.4), the PEDOT/MXene hybrid film is grown on the SPE surface via the electrochemical deposition method. Under the optimized condition, the PEDOT/MXene/SPE-based sensor provides a linear response against SCN from 10 to 100 µM and 0.1 μM to 1000 μM with the lowest limit of detections (LOD) of 1.44 μM and 0.0325 μM by differential pulse voltammetry (DPV) and amperometry, respectively. For accurate detection of SCN, our newly created PEDOT/MXene hybrid film-coated SPE demonstrates excellent sensitivity, selectivity, and repeatability. Ultimately, this novel sensor can be used to detect SCN precisely in environmental and biological samples.
硫氰酸盐（SCN）是氰化物解毒过程中产生的有害副产物。即使含量极少，SCN也会对健康产生负面影响。尽管有多种分析SCN的方法，但几乎从未尝试过高效的电化学方法。在此，作者报告了一种利用聚（3,4-乙撑二氧噻吩）结合MXene（PEDOT/MXene）修饰的丝网印刷电极（SPE）开发的用于SCN的高选择性和灵敏的电化学传感器。拉曼光谱、X射线光电子能谱（XPS）和X射线衍射（XRD）分析支持了PEDOT在MXene表面的有效整合。此外，采用扫描电子显微镜（SEM）来证明MXene和PEDOT/MXene混合膜的形成。为了在磷酸盐缓冲介质（pH 7.4）中特异性检测SCN，通过电化学沉积法在SPE表面生长PEDOT/MXene混合膜。在优化条件下，基于PEDOT/MXene/SPE的传感器对SCN在10至100 μM和0.1 μM至1000 μM范围内呈现线性响应，通过差分脉冲伏安法（DPV）和安培法的最低检测限（LOD）分别为1.44 μM和0.0325 μM。为了准确检测SCN，我们新制备的PEDOT/MXene混合膜包覆的SPE表现出优异的灵敏度、选择性和重复性。最终，这种新型传感器可用于精确检测环境和生物样品中的SCN。
