Oral Health Prev Dent. 2020 Dec 14;18(4):1055-1060. doi: 10.3290/j.ohpd.b871067.
Purpose: The present study analysed the association between anaemia and dental caries in adolescents on the basis of predisposing factors and presence of severely decayed teeth.
Materials and Methods: This observational study included a complex probabilistic sample of adolescents (17-18 years old) enrolled at public schools in São Luís, Brazil (n = 363). Two hypothesis models were tested: (1) anaemia and dental caries are associated given that they share predisposing factors, such as socioeconomic and high sugar consumption, and (2) the presence of severely decayed teeth may increase the susceptibility of patients to anaemia. In the first model, the association between anaemia and the history of dental caries (the outcome number of affected teeth) was analysed by Poisson regression. In the second model, the association between the presence of severely decayed teeth with pulp exposure/necrosis and the outcome anaemia was analysed by logistic regression. Bivariate and multivariate analyses after adjusting for socioeconomic factors and sugar consumption were performed, considering 5% of statistical significance level and using STATA 115.0.
Results: Anaemia was associated with a higher number of affected teeth with a history of dental caries in bivariate (means ratio [MR]: 1.30; 95% confidence intervals [CI95%]: 1.10-1.52; p = 0.001) and multivariate (MR: 1.18; CI95%: 1.01-1.39; p = 0.046) analyses. Severely decayed teeth with pulp exposure/necrosis were associated with anaemia in bivariate (odds ratios [OR]: 5.75; CI95%: 1.97-16.8; p = 0.001)] and multivariate (OR 5.51; CI95%: 1.71-17.74; p = 0.004) analyses.
Conclusion: This study suggests that anaemia and dental caries are associated in a population-based sample of adolescents and that predisposing factors and severely decayed teeth seem to be involved in this association..
本研究基于易感因素和严重龋齿的存在，分析青少年贫血与龋齿之间的关系。
材料与方法：本观察性研究纳入了巴西圣路易斯市公立学校的青少年（17-18 岁）的复杂概率样本（n=363）。测试了两个假设模型：（1）贫血和龋齿存在关联，因为它们具有共同的易感因素，如社会经济状况和高糖摄入；（2）严重龋齿的存在可能会增加患者贫血的易感性。在第一个模型中，通过泊松回归分析贫血与龋齿病史（受影响牙齿的数量结局）之间的关系。在第二个模型中，通过逻辑回归分析严重龋齿伴有牙髓暴露/坏死与贫血结局之间的关系。在调整社会经济因素和糖摄入后进行了单变量和多变量分析，统计学显著性水平为 5%，使用 STATA 115.0 软件进行分析。
结果：贫血与龋齿病史中受影响牙齿数量较多相关，在单变量（平均比数比[MR]：1.30；95%置信区间[CI95%]：1.10-1.52；p=0.001）和多变量（MR：1.18；CI95%：1.01-1.39；p=0.046）分析中均如此。伴有牙髓暴露/坏死的严重龋齿与贫血相关，在单变量（比值比[OR]：5.75；95%置信区间[CI95%]：1.97-16.8；p=0.001）和多变量（OR 5.51；CI95%：1.71-17.74；p=0.004）分析中均如此。
结论：本研究提示，在基于人群的青少年样本中，贫血与龋齿之间存在关联，易感因素和严重龋齿似乎与这种关联有关。
