Krauze Agnieszka, Woźniak Witold, Mlosek Robert Krzysztof
Ultrasound Diagnostic Department, Faculty of Medical Sciences, Medical University of Warsaw, Warsaw, Poland.
First Department of General and Vascular Surgery, Faculty of Medicine, Medical University of Warsaw, Poland.
J Ultrason. 2021;20(83):e254-e260. doi: 10.15557/JoU.2020.0045. Epub 2020 Dec 18.
As the average lifespan becomes longer, the number of cases of chronic shin ulcers is rising, which is slowly becoming a societal problem. Currently, there no methods for objective evaluation of ulcer healing process.
The aim of the study was to assess the use of high-frequency ultrasound to monitor the healing of shin ulcers subjected to laser biostimulation.
The study included 8 patients (4 men and 4 women) aged from 46 to 81 years with 9 shin ulcers in whom the healing process did not progress within 8 weeks despite effective causal treatment. The ulcers were subjected to laser biostimulation. The induced changes were monitored using high-frequency ultrasound and photographic records. Ultrasound examination was used to assess the depth of ulceration and the thickness of granulation tissue, migrating epidermis, subepidermal low-echogenic band (SLEB) and epidermis in the immediate vicinity. The wound severity index and ulcer vascularity were also assessed.
As a result of laser therapy, in 7 out of 9 cases the ulcers healed completely and in the remaining 2 cases ulcer size was reduced. During the ulcer healing process induced by laser therapy, ultrasound examination revealed decreasing ulcer depth, wound severity index and SLEB thickness. Granulation tissue increased in thickness and there was an epidermal formation effect (newly formed epidermis was much thicker than the one surrounding the wound and became thicker as a result of laser therapy sessions). During the healing of ulcers induced by laser therapy no significant changes were observed in ulcer vascularity and thickness of the surrounding epidermis.
High-frequency ultrasound is a useful technique for the imaging of leg ulcers. It allows one to monitor their healing process induced by laser biostimulation. Further research on the subject needs to be pursued.
随着平均寿命的延长,慢性胫骨溃疡的病例数量不断增加,这正逐渐成为一个社会问题。目前,尚无客观评估溃疡愈合过程的方法。
本研究旨在评估高频超声在监测接受激光生物刺激的胫骨溃疡愈合情况中的应用。
本研究纳入了8例年龄在46至81岁之间的患者(4名男性和4名女性),他们共有9处胫骨溃疡,尽管进行了有效的病因治疗,但溃疡愈合过程在8周内仍无进展。对这些溃疡进行激光生物刺激。使用高频超声和摄影记录监测诱导产生的变化。超声检查用于评估溃疡深度、肉芽组织厚度、迁移的表皮、表皮下低回声带(SLEB)以及紧邻区域的表皮厚度。还评估了伤口严重程度指数和溃疡血管情况。
激光治疗后,9例中有7例溃疡完全愈合,其余2例溃疡面积减小。在激光治疗诱导的溃疡愈合过程中,超声检查显示溃疡深度、伤口严重程度指数和SLEB厚度降低。肉芽组织厚度增加,并且有表皮形成效应(新形成的表皮比伤口周围的表皮厚得多,并且由于激光治疗疗程而变厚)。在激光治疗诱导的溃疡愈合过程中,溃疡血管情况和周围表皮厚度未观察到显著变化。
高频超声是一种用于腿部溃疡成像的有用技术。它能够监测激光生物刺激诱导的溃疡愈合过程。对此主题需要进一步研究。