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类固醇激素增强了培养的中国仓鼠卵巢细胞中的姐妹染色单体交换。

Steroid hormones enhanced sister-chromatid exchange in cultured CHO cells.

作者信息

Kochhar T S

机构信息

Division of Mathematics and Sciences, Kentucky State Univesity, Frankfort 40601.

出版信息

Experientia. 1988 Jan 15;44(1):62-3. doi: 10.1007/BF01960247.

DOI:10.1007/BF01960247
PMID:3350124
Abstract

The influence of steroid hormones on the induction of sister-chromatid exchange (SCE) in cultured CHO cells was studied. It was observed that estradiol-17 beta, estriol, estrone and ethynyl estradiol treatments enhanced SCE rates compared to the controls. Overall, these compounds produced a dose response effect. The importance of a detailed study on the long-term genetic effects of steroids on mammalian cells is emphasized.

摘要

研究了甾体激素对培养的中国仓鼠卵巢(CHO)细胞中姐妹染色单体交换(SCE)诱导的影响。观察到,与对照组相比,17β-雌二醇、雌三醇、雌酮和乙炔雌二醇处理可提高SCE率。总体而言,这些化合物产生了剂量反应效应。强调了详细研究甾体激素对哺乳动物细胞长期遗传效应的重要性。

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Steroid hormones enhanced sister-chromatid exchange in cultured CHO cells.类固醇激素增强了培养的中国仓鼠卵巢细胞中的姐妹染色单体交换。
Experientia. 1988 Jan 15;44(1):62-3. doi: 10.1007/BF01960247.
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引用本文的文献

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In situ demonstration of the activity of 3 beta-hydroxysteroid dehydrogenase on steroid hormone secreting cells within the paraaortic lymph nodes of golden hamster.金黄仓鼠主动脉旁淋巴结内类固醇激素分泌细胞上3β-羟基类固醇脱氢酶活性的原位显示
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Enhanced production of micronuclei by hexavalent chromium in cultured CHO cells.六价铬在培养的中国仓鼠卵巢细胞中增强微核的产生。
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本文引用的文献

1
Normal sister-chromatid exchanges in oral contraceptive users.
Mutat Res. 1982 Feb;103(2):161-4. doi: 10.1016/0165-7992(82)90023-9.
2
Further studies on sister-chromatid exchange frequency in users of hormonal contraceptives.
Mutat Res. 1983 Mar;119(3):351-4. doi: 10.1016/0165-7992(83)90184-7.
3
Structural specificity of estrogens in the induction of mitotic chromatid non-disjunction in HeLa cells.雌激素诱导HeLa细胞有丝分裂染色单体不分离的结构特异性
Exp Cell Res. 1967 Oct;48(1):71-81. doi: 10.1016/0014-4827(67)90277-7.
4
New Giemsa method for the differential staining of sister chromatids.用于姐妹染色单体鉴别染色的新吉姆萨方法。
Nature. 1974 Sep 13;251(5471):156-8. doi: 10.1038/251156a0.
5
Inducibility of chromosome aberrations by steroid hormones in cultured Chinese hamster ovary cells.甾体激素对培养的中国仓鼠卵巢细胞染色体畸变的诱导作用
Toxicol Lett. 1985 Dec;29(2-3):201-6. doi: 10.1016/0378-4274(85)90042-6.
6
Chromosome breakage studies in lymphocytes from normal women, pregnant women, and women taking oral contraceptives.对正常女性、孕妇及服用口服避孕药女性的淋巴细胞进行染色体断裂研究。
Am J Obstet Gynecol. 1975 Apr 1;121(7):976-80. doi: 10.1016/0002-9378(75)90921-7.
7
Chromosome aberrations and sister chromatid exchanges in Chinese hamster cells exposed to various chemicals.暴露于各种化学物质的中国仓鼠细胞中的染色体畸变和姐妹染色单体交换。
J Natl Cancer Inst. 1977 Jun;58(6):1635-41. doi: 10.1093/jnci/58.6.1635.
8
Cytological effects of the oral contraceptive.口服避孕药的细胞学效应。
Mutat Res. 1976;39(1):97-110. doi: 10.1016/0165-1110(76)90014-2.
9
The induction of sister-chromatid exchanges in Chinese hamster ovary cells by prolonged exposure to 2-acetylaminofluorene and S-9 mix.通过长时间暴露于2-乙酰氨基芴和S-9混合物诱导中国仓鼠卵巢细胞中的姐妹染色单体交换。
Mutat Res. 1978 Sep;58(1):103-6. doi: 10.1016/0165-1218(78)90100-3.
10
Sister-chromatid exchanges in oral contraceptive users.
Mutat Res. 1979 Oct;68(2):149-52. doi: 10.1016/0165-1218(79)90142-3.