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医用大麻政策与阿片类药物相关的医疗保健利用之间的关联。

The associations of medical marijuana policies with opioid-related health care utilization.

机构信息

College of Pharmacy, University of Georgia, Athens, Georgia, USA.

Department of Economics, University of Louisville, Louisville, Kentucky, USA.

出版信息

Health Serv Res. 2021 Apr;56(2):299-309. doi: 10.1111/1475-6773.13632. Epub 2021 Jan 26.

Abstract

OBJECTIVE

To examine the associations between medical marijuana policies and opioid-related hospitalizations and emergency department visits.

DATA SOURCES

We utilized quarterly rates of hospital discharge data from the Healthcare Cost and Utilization Project's (HCUP) Fast Stats Database from 2005 to 2016 along with state-level sociodemographic data from US Census Bureau and Bureau of Labor Statistics and opioid-related state health policy data from publicly available sources for the analysis.

STUDY DESIGN

Analyses were carried out using a difference-in-differences regression approach. We estimate heterogeneous effects of medical marijuana policies such as initial policy, presence of active dispensary, and home cultivation on opioid-related hospitalizations and emergency department visits related to opioids.

DATA COLLECTION/EXTRACTION METHODS: Publicly available secondary data were collected, linked, and analyzed. Observations with missing values for explanatory variables were excluded from the analysis.

PRINCIPAL FINDINGS

Regression results indicate that type of medical marijuana policy has varying effects on opioid-related hospitalizations and emergency department visits. States that allow home cultivation of medical marijuana experienced significant positive associations with opioid-related hospitalizations and emergency department visits, while no effect was observed with medical marijuana dispensaries. Moreover, recreational marijuana policies were positively associated with opioid-related hospitalizations.

CONCLUSIONS

The findings indicate that the effects of medical marijuana policies on opioid-related hospitalizations and emergency department visits vary depending on the type of medical marijuana policy. Our findings indicate that the implementation of home cultivation of marijuana is positively associated with hospitalizations and emergency department visits related to opioids, suggesting that easier access to marijuana among opioid users may result in adverse health conditions that need treatment.

摘要

目的

考察医用大麻政策与阿片类药物相关住院和急诊就诊之间的关联。

资料来源

我们利用 2005 年至 2016 年医疗保健成本和利用项目(HCUP)FastStats 数据库的季度住院数据,以及美国人口普查局和劳工统计局的州级社会人口数据,并利用公开来源的阿片类药物相关州卫生政策数据进行分析。

研究设计

采用差分法回归方法进行分析。我们估计医用大麻政策的异质效应,如初始政策、现有活动药房和家庭种植对阿片类药物相关住院和与阿片类药物相关的急诊就诊的影响。

资料收集/提取方法:收集、链接和分析公开的二手数据。对解释变量存在缺失值的观察值从分析中排除。

主要发现

回归结果表明,医用大麻政策的类型对阿片类药物相关住院和急诊就诊有不同的影响。允许医用大麻家庭种植的州与阿片类药物相关住院和急诊就诊显著正相关,而医用大麻药房则没有观察到这种影响。此外,娱乐用大麻政策与阿片类药物相关住院呈正相关。

结论

研究结果表明,医用大麻政策对阿片类药物相关住院和急诊就诊的影响因医用大麻政策的类型而异。我们的研究结果表明,大麻家庭种植的实施与阿片类药物相关的住院和急诊就诊呈正相关,这表明阿片类药物使用者更容易获得大麻可能会导致需要治疗的不良健康状况。

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State marijuana laws and opioid overdose mortality.州大麻法律与阿片类药物过量死亡率。
Inj Epidemiol. 2019 Sep 2;6:38. doi: 10.1186/s40621-019-0213-z. eCollection 2019.
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Cannabis Use and Risk of Prescription Opioid Use Disorder in the United States.美国大麻使用与处方阿片类药物使用障碍风险
Am J Psychiatry. 2018 Jan 1;175(1):47-53. doi: 10.1176/appi.ajp.2017.17040413. Epub 2017 Sep 26.

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