Samuel D, Sattouf E, Degott C, Benhamou J P
Service d'Hépatologie et Unité de Recherches de Physiopathologie Hépatique (INSERM), Clichy.
Gastroenterol Clin Biol. 1988 Jan;12(1):39-42.
The prevalence of cholelithiasis was estimated in 434 cirrhotic patients and 1582 non cirrhotic patients necropsied at Hôpital Beaujon from 1976 to 1984. The overall prevalence of cholelithiasis was significantly higher in cirrhotic than in non cirrhotic patients, 26.3 p. 100 and 20.3 p. 100, respectively. The prevalence of cholelithiasis was higher in cirrhotic than in non cirrhotic patients, whether male or female and at any age, except in women over 60 years and in men over 80 years; in these groups, the prevalence of cholelithiasis in non cirrhotic patients was especially high and therefore did not significantly differ from that in cirrhotic patients. The cause of cirrhosis did not significantly influence the prevalence of cholelithiasis; however, although the number of studied patients was small, the prevalence of cholelithiasis seemed to be particularly high in primary biliary cirrhosis. The prevalence of cholecystectomy was lower in cirrhotic than in non cirrhotic patients, which suggests that cholelithiasis might be less often symptomatic and/or less often complicated in the former than in the latter.
对1976年至1984年在博若莱医院接受尸检的434例肝硬化患者和1582例非肝硬化患者的胆结石患病率进行了评估。肝硬化患者的胆结石总体患病率显著高于非肝硬化患者,分别为26.3%和20.3%。无论男性还是女性,在任何年龄段,肝硬化患者的胆结石患病率均高于非肝硬化患者,但60岁以上女性和80岁以上男性除外;在这些人群中,非肝硬化患者的胆结石患病率特别高,因此与肝硬化患者的患病率无显著差异。肝硬化的病因对胆结石患病率无显著影响;然而,尽管研究的患者数量较少,但原发性胆汁性肝硬化患者的胆结石患病率似乎特别高。肝硬化患者的胆囊切除术患病率低于非肝硬化患者,这表明前者的胆结石症状可能较少和/或并发症较少。