Acalovschi M, Badea R, Dumitraşcu D, Varga C
Department of Gastroenterology, Institute of Medicine, Cluj-Napoca, Romania.
Am J Gastroenterol. 1988 Sep;83(9):954-6.
A sonographic prospective study of the prevalence of gallstones was performed in 140 patients with liver cirrhosis and in 140 controls. Gallstones were found more often in cirrhotic patients (29.2%) than in controls (13.6%) (p less than 0.01). Their prevalence increased with age. The ratio of women to men in cirrhotics was the same as in the general population, with a higher prevalence in women. The prevalence of gallstones increased in decompensated liver disease. There was a significantly higher prevalence of both hypersplenism and hemolysis in cirrhosis. No difference was found in gallstone prevalence in relation to cirrhosis etiology. This prospective study confirms, by means of sonography, the high prevalence of cholelithiasis in liver cirrhosis, and extends the previous data about the lithogenic risk factors in this disease.
对140例肝硬化患者和140例对照者进行了一项关于胆结石患病率的超声前瞻性研究。肝硬化患者中胆结石的发现率（29.2%）高于对照组（13.6%）（p<0.01）。其患病率随年龄增长而增加。肝硬化患者中女性与男性的比例与一般人群相同，女性患病率更高。失代偿性肝病患者胆结石的患病率增加。肝硬化患者脾功能亢进和溶血的患病率均显著更高。在胆结石患病率方面，未发现与肝硬化病因有关的差异。这项前瞻性研究通过超声检查证实了肝硬化患者胆石症的高患病率，并扩展了此前关于该疾病结石形成危险因素的数据。
