Ichiyanaqui C, Monge E, Huamán C, Flores C, Beteta O, Soto W
Servicio de Gastroenterología, Hospital Nacional Daniel Aclides Carrión, Callao, Perú.
Rev Gastroenterol Peru. 1996 Jan-Apr;16(1):43-7.
We retrospectively studied 67 cirrhotic patients hospitalized in the service of gastroenterology of Hospital Daniel A. Carrión, Callao, Perú, between June 1993 and July 1995, aimed to determine the frequency of cholelithiasis and its main clinical and epidemiological features. Twelve out of 67 cirrhotic patients (17.91%) had cholelithiasis. 24% of women and 14.3% of men were affected (p > 0.05). The mean age of women and men were 57.33 and 57.5 years old respectively (range: 41-67 years old). The frequency of cholelithiasis did not increase with age and the proportionally most affected age group was 41-50 years (33.33%). Alcoholic etiology was the most often in cirrhotic patients with cholelithiasis (41.67%). The severity of liver disease influenced in the cholelithiasis frequency (p = 0.001) and 33.33% of patients with gallstones were in grade C of Child Pugh Score. Two thirds of patients were asymptomatic. We conclude: 1. Cholelithiasis in our cirrhotic patients more prevalent than in general population (17.91% vs 0.7-5%). 2. Age did not influence in cholelithiasis prevalence in our cirrhotic patients. 3. The severity of liver disfunction influenced in highly significant way (p = 0.001) on cholelithiasis prevalence. 4. Cirrhotic patients with gallstones had mostly (66.67%) an asymptomatic course.
我们回顾性研究了1993年6月至1995年7月期间在秘鲁卡亚俄市丹尼尔·A·卡里翁医院胃肠病科住院的67例肝硬化患者,旨在确定胆结石的发生率及其主要临床和流行病学特征。67例肝硬化患者中有12例(17.91%)患有胆结石。女性患者的患病率为24%,男性患者为14.3%(p>0.05)。女性和男性的平均年龄分别为57.33岁和57.5岁(范围:41 - 67岁)。胆结石的发生率并不随年龄增加而升高,受影响比例最高的年龄组为41 - 50岁(33.33%)。酒精性病因是患有胆结石的肝硬化患者中最常见的病因(41.67%)。肝脏疾病的严重程度影响胆结石的发生率(p = 0.001),33.33%的胆结石患者属于Child - Pugh评分C级。三分之二的患者无症状。我们得出以下结论:1. 我们的肝硬化患者中胆结石的患病率高于普通人群(17.91%对0.7 - 5%)。2. 年龄对我们的肝硬化患者中胆结石的患病率没有影响。3. 肝功能障碍的严重程度对胆结石的患病率有极显著影响(p = 0.001)。4. 患有胆结石的肝硬化患者大多(66.67%)病程无症状。