Kudo Risa, Sekine Masayuki, Yamaguchi Manako, Hara Megumi, Hanley Sharon J B, Ueda Yutaka, Yagi Asami, Adachi Sosuke, Kurosawa Megumi, Miyagi Etsuko, Enomoto Takayuki
Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510, Japan.
Department of Preventive Medicine, Faculty of Medicine, Saga University, Saga 849-8501, Japan.
Vaccines (Basel). 2021 Jan 25;9(2):87. doi: 10.3390/vaccines9020087.
Recommendations for HPV vaccines were suspended in 2013 due to unfounded safety fears in Japan. We aimed to clarify the differences between vaccinated and unvaccinated females in their awareness, knowledge, and behaviors toward cervical cancer, HPV vaccination and sex. Questionnaires were administered online to women aged 16 to 20. We conducted investigations for the following: awareness, knowledge, and actions for cervical cancer, HPV vaccination, and sexual activity, as well as items related to participants' social background. The survey in 828 girls revealed three points. The first is that more than half of the surveyed Japanese girls had poor knowledge about cervical cancer screening, HPV, or HPV vaccines. The second is that those in the unvaccinated group had a particularly poor knowledge of the subject and tended to have higher sexual activity. The final is that only 0.5% of the girls experienced changes in awareness about sexual activity after vaccination. In conclusion, this is the first large-scale survey analyzing the association between HPV vaccination and sexual activity in Japanese girls. Not only do unvaccinated girls not benefit from vaccines, but they also tend to engage in high-risk sexual behavior, and thus it is even more important to provide information on the effectiveness of vaccines and the usefulness of cancer screening.
2013年，由于日本毫无根据的安全担忧，人乳头瘤病毒（HPV）疫苗的接种建议被暂停。我们旨在阐明接种疫苗和未接种疫苗的女性在对宫颈癌、HPV疫苗接种及性行为的认知、知识和行为方面的差异。对16至20岁的女性进行了在线问卷调查。我们对以下方面进行了调查：对宫颈癌、HPV疫苗接种和性活动的认知、知识及行动，以及与参与者社会背景相关的项目。对828名女孩的调查揭示了三点。第一，超过一半接受调查的日本女孩对宫颈癌筛查、HPV或HPV疫苗的了解不足。第二，未接种疫苗组的女孩对该主题的了解尤其匮乏，且往往有更高的性活动频率。最后一点是，只有0.5%的女孩在接种疫苗后对性活动的认知有所改变。总之，这是首次分析日本女孩中HPV疫苗接种与性活动之间关联的大规模调查。未接种疫苗的女孩不仅无法从疫苗中受益，而且还往往从事高风险性行为，因此提供有关疫苗有效性和癌症筛查有用性的信息就更为重要。
