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Presence of SARS-CoV-2 Transcripts in the Choroid Plexus of MS and Non-MS Patients With COVID-19.

作者信息

Fuchs Vidmante, Kutza Michael, Wischnewski Sven, Deigendesch Nikolaus, Lutz Luc, Kulsvehagen Laila, Ricken Gerda, Kappos Ludwig, Tzankov Alexandar, Hametner Simon, Frank Stephan, Schirmer Lucas, Pröbstel Anne-Katrin

机构信息

From the Multiple Sclerosis Center (V.F., L.L., L. Kulsvehagen, L. Kappos), Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research, and Biomedicine, University Hospital and University of Basel, Switzerland; Department of Neurology (M.K., S.W., L.S.), Medical Faculty Mannheim, Heidelberg University, Germany; Pathology (N.D., A.T., S.F.), Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Switzerland; Department of Neurology (G.R., S.H.), Division of Neuropathology and Neurochemistry, Medical University Vienna, Austria; Mannheim Center for Translational Neuroscience and Institute for Innate Immunoscience (L.S.), Medical Faculty Mannheim, Heidelberg University, Germany; and Interdisciplinary Center for Neurosciences (L.S.), Heidelberg University, Germany.

出版信息

Neurol Neuroimmunol Neuroinflamm. 2021 Jan 27;8(2). doi: 10.1212/NXI.0000000000000957. Print 2021 Mar 4.

DOI:10.1212/NXI.0000000000000957
PMID:33504636
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7862096/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ccd/7862096/471cb9a602bc/NEURIMMINFL2020035428f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ccd/7862096/471cb9a602bc/NEURIMMINFL2020035428f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ccd/7862096/471cb9a602bc/NEURIMMINFL2020035428f1.jpg

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本文引用的文献

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Cell Stem Cell. 2020 Dec 3;27(6):951-961.e5. doi: 10.1016/j.stem.2020.10.001. Epub 2020 Oct 13.
2
Correlates of critical illness-related encephalopathy predominate postmortem COVID-19 neuropathology.危重症相关脑病的相关因素在新冠病毒疾病尸检神经病理学中占主导地位。
Acta Neuropathol. 2020 Oct;140(4):583-586. doi: 10.1007/s00401-020-02213-y. Epub 2020 Aug 26.
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Microvascular injury and hypoxic damage: emerging neuropathological signatures in COVID-19.
Fluids Barriers CNS. 2023 Oct 24;20(1):76. doi: 10.1186/s12987-023-00479-4.
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Direct and indirect impact of SARS-CoV-2 on the brain.SARS-CoV-2 对大脑的直接和间接影响。
Hum Genet. 2023 Aug;142(8):1317-1326. doi: 10.1007/s00439-023-02549-x. Epub 2023 Apr 1.
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The Latest Cellular and Molecular Mechanisms of COVID-19 on Non-Lung Organs.新冠病毒对非肺部器官影响的最新细胞和分子机制
Brain Sci. 2023 Feb 27;13(3):415. doi: 10.3390/brainsci13030415.
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Microglia innate immune response contributes to the antiviral defense and blood-CSF barrier function in human choroid plexus organoids during HSV-1 infection.小胶质细胞固有免疫反应有助于在 HSV-1 感染期间人脉络丛类器官中的抗病毒防御和血脑屏障功能。
J Med Virol. 2023 Feb;95(2):e28472. doi: 10.1002/jmv.28472.
7
Year in Review.年度回顾
Neurol Neuroimmunol Neuroinflamm. 2023 Jan 3;10(1). doi: 10.1212/NXI.0000000000200076. Print 2023 Jan.
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Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study.严重神经新冠与外周免疫特征、自身免疫和神经退行性变相关:一项前瞻性横断面研究。
Nat Commun. 2022 Nov 9;13(1):6777. doi: 10.1038/s41467-022-34068-0.
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Fluids Barriers CNS. 2022 Sep 10;19(1):75. doi: 10.1186/s12987-022-00372-6.
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Mechanisms of coronavirus infectious disease 2019-related neurologic diseases.新型冠状病毒感染相关神经系统疾病发病机制。
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N Engl J Med. 2018 Jan 11;378(2):169-180. doi: 10.1056/NEJMra1401483.