Long-term Durability of Coil Embolization for Unruptured Aneurysm after Introduction of the Neck-bridge Stent: Comparison between the Pre-stent Era and the Stent Era.

More complex aneurysms can be treated by coil embolization with neck-bridge stent assistance. However, concerns about postprocedural ischemic or hemorrhagic complications remain. In this study, we assessed the long-term durability after introduction of neck-bridge stent in the context of coil embolization for unruptured aneurysm by comparing re-treatment and neurological events between the pre-stent and stent eras. Unruptured aneurysms treated by coil embolization between April 2005 and May 2018 were analyzed retrospectively. We divided cases into two groups: the pre-stent era and the stent era. The cumulative rate of re-treatment and neurological events were assessed and compared. During the period, 177 aneurysms were treated in the pre-stent era and 354 aneurysms were treated in the stent era. The median follow-up was 55 months. In the stent era, the dome/neck (D/N) ratio was significantly lower (P <0.001) and the number of aneurysms located at the posterior circulation was higher (P <0.001). A stent was used in 31.92% of cases in the stent era. The cumulative rate of re-treatment was significantly higher in the pre-stent era than it was in the stent era in univariate and multivariate analyses (P = 0.008, P = 0.008, respectively). The cumulative rate of neurological events was not significantly different between the two groups. The re-treatment rate has been improved without increasing neurological complications after introduction of the neck-bridge stent.