Uchiyama Shinichiro, Yamazaki Masako, Ishikawa Tatsuya, Yamaguchi Koji, Kawamata Takakazu
Clinical Research Center for Medicine, International University of Health and Welfare, Center for Brain and Cerebral Vessels, Sanno Hospital and Sanno Medical Center, Tokyo, Japan.
Department of Neurology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan.
Case Rep Neurol. 2020 Dec 14;12(Suppl 1):137-142. doi: 10.1159/000505967. eCollection 2020 Sep-Dec.
Moyamoya disease is an uncommon vascular disease, which causes obstruction and stenosis of arteries of the circle of Willis, and preferentially affects children and young adults. This disease is seen across the world, but is more common in East Asia. It may cause hemorrhagic or ischemic stroke, or transient ischemic attack. If symptoms or cerebral blood flow become worse, revascularization surgery is recommended. We present 2 cases of moyamoya disease who underwent bypass surgery. We also discuss the epidemiology, pathology, genomics, and symptomatology as well as diagnosis, and management of moyamoya disease.
烟雾病是一种罕见的血管疾病，它会导致 Willis 环动脉的阻塞和狭窄，并且更易影响儿童和年轻人。这种疾病在世界各地都有发现，但在东亚更为常见。它可能会导致出血性或缺血性中风，或短暂性脑缺血发作。如果症状或脑血流恶化，建议进行血管重建手术。我们介绍了 2 例接受搭桥手术的烟雾病病例。我们还讨论了烟雾病的流行病学、病理学、基因组学、症状学以及诊断和治疗。
