Chen Hui, Tan Pei-Shan, Li Chun-Ping, Chen Bi-Zhen, Xu Yu-Qin, He Yan-Qin, Ke Xiao
Department of the Key Specialty of Spleen and Stomach, The Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Department of the Internal Medicine, Fuzhou Economic and Technological Development Zone Hospital, Fuzhou, China.
Evid Based Complement Alternat Med. 2021 Jan 12;2021:1416236. doi: 10.1155/2021/1416236. eCollection 2021.
Results showed the overall structure of gut microbiome has no significant difference between experimental and control groups. In the genus level, the abundance of and is higher in the experiment group than in the control, whereas that of is less. The 16S KEGG function prediction suggested that Parkinson disease, retinol metabolism, and arachidonic acid metabolism could explain the biological function of different gut microbiome. Furthermore, cytokines in the serum showed a correlation with the abundance of in CFC.
AMT could change the composition of gut microbiome which is associated with cytokines in CFC patients.
结果显示,实验组和对照组肠道微生物群的整体结构无显著差异。在属水平上,实验组中[具体菌属1]和[具体菌属2]的丰度高于对照组,而[具体菌属3]的丰度较低。16S KEGG功能预测表明,帕金森病、视黄醇代谢和花生四烯酸代谢可以解释不同肠道微生物群的生物学功能。此外,血清中的细胞因子与CFC中[相关菌属]的丰度呈相关性。
AMT可改变CFC患者肠道微生物群的组成,且这与细胞因子有关。