ENIGMA 脑损伤工作组：方法、挑战和潜在益处。
The ENIGMA Brain Injury working group: approach, challenges, and potential benefits.
机构信息
TBICC, Department of Neurology, University of Utah School of Medicine, Salt Lake City, UT, USA.
George E. Wahlen VA Medical Center, Salt Lake City, UT, USA.
出版信息
Brain Imaging Behav. 2021 Apr;15(2):465-474. doi: 10.1007/s11682-021-00450-7. Epub 2021 Jan 27.
Abstract
The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium brings together researchers from around the world to try to identify the genetic underpinnings of brain structure and function, along with robust, generalizable effects of neurological and psychiatric disorders. The recently-formed ENIGMA Brain Injury working group includes 10 subgroups, based largely on injury mechanism and patient population. This introduction to the special issue summarizes the history, organization, and objectives of ENIGMA Brain Injury, and includes a discussion of strategies, challenges, opportunities and goals common across 6 of the subgroups under the umbrella of ENIGMA Brain Injury. The following articles in this special issue, including 6 articles from different subgroups, will detail the challenges and opportunities specific to each subgroup.
摘要
增强神经影像学遗传学的荟萃分析（ENIGMA）联合会汇集了来自世界各地的研究人员，试图确定大脑结构和功能的遗传基础，以及神经和精神疾病的强大、可推广的影响。最近成立的 ENIGMA 脑损伤工作组包括 10 个分组，主要基于损伤机制和患者人群。本特刊介绍总结了 ENIGMA 脑损伤的历史、组织和目标，并讨论了 ENIGMA 脑损伤下的 6 个分组共有的策略、挑战、机遇和目标。本特刊中的以下文章，包括来自不同分组的 6 篇文章，将详细介绍每个分组的具体挑战和机遇。
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