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本文引用的文献

1
Coordinating Global Multi-Site Studies of Military-Relevant Traumatic Brain Injury: Opportunities, Challenges, and Harmonization Guidelines.协调全球与军事相关的创伤性脑损伤多中心研究：机遇、挑战和协调准则。
Brain Imaging Behav. 2021 Apr;15(2):585-613. doi: 10.1007/s11682-020-00423-2. Epub 2021 Jan 7.
2
The clinical utility of proton magnetic resonance spectroscopy in traumatic brain injury: recommendations from the ENIGMA MRS working group.质子磁共振波谱在创伤性脑损伤中的临床应用：来自 ENIGMA MRS 工作组的建议。
Brain Imaging Behav. 2021 Apr;15(2):504-525. doi: 10.1007/s11682-020-00330-6.
3
Ethical issues in global neuroimaging genetics collaborations.全球神经影像学遗传学合作中的伦理问题。
Neuroimage. 2020 Nov 1;221:117208. doi: 10.1016/j.neuroimage.2020.117208. Epub 2020 Jul 29.
4
ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries.ENIGMA 与全球神经科学：十年来，该计划在 40 多个国家开展了针对大脑在健康和疾病中的大规模研究。
Transl Psychiatry. 2020 Mar 20;10(1):100. doi: 10.1038/s41398-020-0705-1.
5
Altered white matter microstructural organization in posttraumatic stress disorder across 3047 adults: results from the PGC-ENIGMA PTSD consortium.3047名成年人创伤后应激障碍患者的白质微观结构组织改变：PGC-ENIGMA创伤后应激障碍联盟的研究结果
Mol Psychiatry. 2021 Aug;26(8):4315-4330. doi: 10.1038/s41380-019-0631-x. Epub 2019 Dec 19.
6
White matter abnormalities across the lifespan of schizophrenia: a harmonized multi-site diffusion MRI study.精神分裂症全生命周期的脑白质异常：一项多中心弥散磁共振成像研究
Mol Psychiatry. 2020 Dec;25(12):3208-3219. doi: 10.1038/s41380-019-0509-y. Epub 2019 Sep 11.
7
Interactive impact of childhood maltreatment, depression, and age on cortical brain structure: mega-analytic findings from a large multi-site cohort.童年期虐待、抑郁和年龄对大脑皮质结构的交互影响：来自大型多中心队列的汇总分析结果
Psychol Med. 2020 Apr;50(6):1020-1031. doi: 10.1017/S003329171900093X. Epub 2019 May 14.
8
The Ivy League-Big Ten Epidemiology of Concussion Study: A Report on Methods and First Findings.常春藤联盟-十大联盟脑震荡流行病学研究：方法和初步发现报告。
Am J Sports Med. 2019 Apr;47(5):1236-1247. doi: 10.1177/0363546519830100.
9
Analytic Tools for Post-traumatic Epileptogenesis Biomarker Search in Multimodal Dataset of an Animal Model and Human Patients.在动物模型和人类患者多模态数据集中寻找创伤后癫痫发生生物标志物的分析工具
Front Neuroinform. 2018 Dec 20;12:86. doi: 10.3389/fninf.2018.00086. eCollection 2018.
10
Mega-Analysis of Gray Matter Volume in Substance Dependence: General and Substance-Specific Regional Effects.物质依赖的灰质体积的 Mega 分析：一般和物质特异性的区域性效应。
Am J Psychiatry. 2019 Feb 1;176(2):119-128. doi: 10.1176/appi.ajp.2018.17040415. Epub 2018 Oct 19.

ENIGMA 脑损伤工作组：方法、挑战和潜在益处。

The ENIGMA Brain Injury working group: approach, challenges, and potential benefits.

机构信息

TBICC, Department of Neurology, University of Utah School of Medicine, Salt Lake City, UT, USA.

George E. Wahlen VA Medical Center, Salt Lake City, UT, USA.

出版信息

Brain Imaging Behav. 2021 Apr;15(2):465-474. doi: 10.1007/s11682-021-00450-7. Epub 2021 Jan 27.

DOI:10.1007/s11682-021-00450-7
PMID:33506440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8035294/
Abstract

The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium brings together researchers from around the world to try to identify the genetic underpinnings of brain structure and function, along with robust, generalizable effects of neurological and psychiatric disorders. The recently-formed ENIGMA Brain Injury working group includes 10 subgroups, based largely on injury mechanism and patient population. This introduction to the special issue summarizes the history, organization, and objectives of ENIGMA Brain Injury, and includes a discussion of strategies, challenges, opportunities and goals common across 6 of the subgroups under the umbrella of ENIGMA Brain Injury. The following articles in this special issue, including 6 articles from different subgroups, will detail the challenges and opportunities specific to each subgroup.

摘要

增强神经影像学遗传学的荟萃分析（ENIGMA）联合会汇集了来自世界各地的研究人员，试图确定大脑结构和功能的遗传基础，以及神经和精神疾病的强大、可推广的影响。最近成立的 ENIGMA 脑损伤工作组包括 10 个分组，主要基于损伤机制和患者人群。本特刊介绍总结了 ENIGMA 脑损伤的历史、组织和目标，并讨论了 ENIGMA 脑损伤下的 6 个分组共有的策略、挑战、机遇和目标。本特刊中的以下文章，包括来自不同分组的 6 篇文章，将详细介绍每个分组的具体挑战和机遇。