Boehncke Wolf-Henning, Stalder Romaine, Brembilla Nicolò Costantino
Service de dermatologie et vénéréologie, Département des spécialités de médecine, HUG, 1211 Genève 14.
Département de pathologie et immunologie, CMU, Université de Genève, 1211 Genève 4.
Rev Med Suisse. 2021 Jan 27;17(723):184-187.
Atopic dermatitis and psoriasis are two diseases that are thought to be distinct from each other, both clinically as well as pathogenetically. Substantial progress has been made in their treatment through the introduction of targeted therapies, blocking key steps in the respective pathogenetic pathways. Interestingly, introduction of a specific therapy for one of these diseases can occasionally trigger onset of the other. This observation helps to better understand the pathophysiology of both diseases and directly impacts their management.
特应性皮炎和银屑病是两种在临床和发病机制上都被认为彼此不同的疾病。通过引入靶向治疗，阻断各自发病途径中的关键步骤，它们的治疗取得了重大进展。有趣的是，针对其中一种疾病引入特定治疗有时会引发另一种疾病的发作。这一观察结果有助于更好地理解这两种疾病的病理生理学，并直接影响它们的治疗管理。
