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美国多发性硬化症成年人对 COVID-19 疫苗接种的意愿。

Willingness to obtain COVID-19 vaccination in adults with multiple sclerosis in the United States.

机构信息

Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA.

Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA.

出版信息

Mult Scler Relat Disord. 2021 Apr;49:102788. doi: 10.1016/j.msard.2021.102788. Epub 2021 Jan 22.

Abstract

BACKGROUND

As vaccines for the coronavirus become available, it will be important to know the rate of COVID-19 vaccine acceptability in adults with multiple sclerosis (MS), given that vaccination will be a key strategy for preventing SARS-CoV-2 infections. Using a national sample of adults with MS in the United States obtained early in the COVID-19 pandemic, the current study aimed to: (1) assess willingness to get a COVID-19 vaccine when available; (2) determine demographic, MS, and psychosocial correlates of vaccine willingness; and (3) measure where people with MS get their COVID-19 information and their perceived trustworthiness of such sources, which may influence COVID-19 vaccine willingness.

METHODS

Adults with MS (N = 486) living in the United States completed a cross-sectional online survey (between 10 April 2020 and 06 May 2020) about their willingness to receive a COVID-19 vaccination once available. Participants also completed measures to describe the sample and to assess factors potentially related to vaccine willingness, including demographics, MS-specific variables, psychological measures, COVID-19 information sources, and perceived trustworthiness of their information sources.

RESULTS

Approximately two-thirds of the participants (66.0%) reported a willingness to obtain a future COVID-19 vaccine, whereas 15.4%of the sample was unwilling. Greater willingness to receive the vaccine was associated with having a higher level of education and holding a higher perception of one's risk of catching COVID-19. Participants reported accessing COVID-19 information from many different sources. Approximately a third (31.6%) of the sample reported getting their information from healthcare providers. Healthcare providers and the National MS Society had the highest perceived trustworthiness for COVID-19 information. The perceived trustworthiness of information sources was highly associated with vaccine willingness.

CONCLUSION

Early in the pandemic, willingness to get a COVID-19 vaccine was not universal in this large sample or people living with MS. Vaccine willingness was associated with a few variables including education level, perceived risk for COVID-19 infection, and trust in COVID-19 information sources. These results have important implications for guiding healthcare providers and the MS community as COVID-19 vaccines become widely available.

摘要

背景

随着冠状病毒疫苗的推出,了解患有多发性硬化症(MS)的成年人对 COVID-19 疫苗的接受率将非常重要,因为接种疫苗将是预防 SARS-CoV-2 感染的关键策略。本研究利用美国 COVID-19 大流行早期获得的全国性 MS 成年人样本,旨在:(1)评估在获得 COVID-19 疫苗时的接种意愿;(2)确定疫苗接种意愿的人口统计学、MS 和心理社会相关因素;(3)衡量 MS 患者从何处获得 COVID-19 信息及其对这些信息源的信任程度,这些因素可能会影响 COVID-19 疫苗的接种意愿。

方法

居住在美国的 MS 成年人(N=486)在 2020 年 4 月 10 日至 5 月 6 日期间完成了一项关于他们在获得 COVID-19 疫苗后接种意愿的横断面在线调查。参与者还完成了描述样本的措施,以及评估可能与疫苗接种意愿相关的因素,包括人口统计学、MS 特定变量、心理测量、COVID-19 信息来源以及对信息来源的信任程度。

结果

大约三分之二的参与者(66.0%)表示愿意接受未来的 COVID-19 疫苗接种,而样本中有 15.4%的人不愿意接种。更高的接种意愿与受教育程度更高和对感染 COVID-19 的风险更高的认知有关。参与者报告从许多不同的来源获取 COVID-19 信息。大约三分之一(31.6%)的样本报告从医疗保健提供者那里获取信息。医疗保健提供者和国家多发性硬化症协会(National MS Society)对 COVID-19 信息的信任度最高。信息来源的可信度与疫苗接种意愿高度相关。

结论

在大流行早期,在这个大型样本或患有 MS 的人群中,接受 COVID-19 疫苗的意愿并不普遍。疫苗接种意愿与一些变量有关,包括教育水平、对 COVID-19 感染的风险认知以及对 COVID-19 信息来源的信任。这些结果对指导医疗保健提供者和 MS 社区在 COVID-19 疫苗广泛可用时具有重要意义。

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