Deschacht J, Devroey P, Camus M, Khan I, Smitz J, Staessen C, Van Waesberghe L, Wisanto A, Van Steirteghem A C
Centre for Reproductive Medicine, Vrije Universiteit Brussel, Belgium.
Hum Reprod. 1988 Jan;3(1):105-8. doi: 10.1093/oxfordjournals.humrep.a136638.
When previous attempts at in-vitro fertilization using semen from the husband failed, a subsequent IVF attempt was performed using husband and donor sperm in order to compare fertilization and embryo formation after insemination with husband and donor sperm of the same oocyte population. Significantly more eggs were fertilized in patients suffering from andrological and idiopathic infertility when donor sperm were used. No differences were seen in patients with tubal infertility. In the andrological group, the embryos fertilized by the husband showed significantly more fragmentation. No pregnancies were established when husband-fertilized oocytes (embryos) were replaced in the andrological and idiopathic infertility group. This study suggested that an IVF trial using husband and donor sperm might be indicated in couples suffering from andrological or idiopathic infertility in whom no fertilization occurred in a previous cycle using sperm from the husband.
当先前使用丈夫精液进行体外受精的尝试失败后，随后进行了一次体外受精尝试，使用丈夫和供体精子，以便比较同一卵母细胞群体经丈夫精子和供体精子授精后的受精和胚胎形成情况。在患有男性不育症和特发性不育症的患者中，使用供体精子时受精的卵子明显更多。输卵管性不育患者未见差异。在男性不育症组中，由丈夫精子受精的胚胎显示出明显更多的碎片。在男性不育症和特发性不育症组中，当植入由丈夫精子受精的卵母细胞（胚胎）时未成功妊娠。这项研究表明，对于患有男性不育症或特发性不育症且在前一周期使用丈夫精子未发生受精的夫妇，可能需要进行使用丈夫和供体精子的体外受精试验。
