Azem F, Botchan A, Yaron Y, Lessing J B, Har-toov J, Yavetz H, Yovel I, Amit A
In Vitro Fertilization/Embryo Transfer Unit, Serlin Maternity Hospital, Tel Aviv Sourasky Medical Center, Israel.
Fertil Steril. 1994 Jun;61(6):1088-91. doi: 10.1016/s0015-0282(16)56761-2.
To examine the IVF-ET outcome of couples with unexplained infertility treated by husband versus donor sperm.
A retrospective analysis of the IVF-ET outcome of couples with unexplained infertility treated by either husband or donor sperm and in a subgroup of patients treated simultaneously by husband and donor sperm.
IVF Unit, Serlin Maternity Hospital, Tel Aviv, Israel.
Couples diagnosed as having unexplained infertility underwent IVF at our Unit; included were 96 couples treated by husband insemination (group A), 27 couples who received donor insemination because of azoospermia (group B), and 8 couples who sought donor insemination after having previously failed IVF (group C).
No statistically significant difference was found between groups A and B regarding age of the females, duration of infertility, number of IVF cycles, fertilization rate, number of ETs, and pregnancy rate. Oocytes collected in group C were subdivided further into two groups: 45 were incubated with husband sperm and 46 were incubated with donor sperm. Fertilization rates were 46.6% and 50%, respectively. One pregnancy occurred.
In couples with unexplained infertility who had undergone IVF-ET with husband insemination, the fertilization and pregnancy rates were similar to those of couples who were treated by donor sperm.
探讨采用丈夫精子与供体精子治疗不明原因不孕夫妇的体外受精-胚胎移植（IVF-ET）结局。
对采用丈夫精子或供体精子治疗的不明原因不孕夫妇的IVF-ET结局进行回顾性分析，并对同时采用丈夫精子和供体精子治疗的患者亚组进行分析。
以色列特拉维夫塞尔林妇产医院体外受精科。
被诊断为不明原因不孕的夫妇在本单位接受IVF治疗；包括96对采用丈夫精液人工授精的夫妇（A组），27对因无精子症接受供体精液人工授精的夫妇（B组），以及8对之前IVF失败后寻求供体精液人工授精的夫妇（C组）。
A组和B组在女性年龄、不孕持续时间、IVF周期数、受精率、胚胎移植数和妊娠率方面未发现统计学上的显著差异。C组收集的卵母细胞进一步分为两组：45个与丈夫精子一起培养，46个与供体精子一起培养。受精率分别为46.6%和50%。发生了1例妊娠。
在采用丈夫精液进行IVF-ET的不明原因不孕夫妇中，受精率和妊娠率与采用供体精子治疗的夫妇相似。
