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近期感染 COVID-19 后，尽管进行了最佳抗凝治疗，但仍反复发作慢性血栓栓塞性疾病。

Recurrent chronic thromboembolic disease despite optimal anticoagulation in setting of recent COVID-19 infection.

机构信息

Internal Medicine, Cooper University Health Care, Camden, New Jersey, USA

Internal Medicine, Cooper University Health Care, Camden, New Jersey, USA.

出版信息

BMJ Case Rep. 2021 Jan 28;14(1):e238733. doi: 10.1136/bcr-2020-238733.

DOI:10.1136/bcr-2020-238733
PMID:33509878
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7844927/
Abstract

We present a case of a 38-year-old man with a history of chronic thromboembolic pulmonary hypertension on therapeutic anticoagulation and recent hospitalisation for COVID-19 disease who was hospitalised for recurrent acute pulmonary embolism despite therapeutic anticoagulation with warfarin (International Normalized Ratio (INR) of 3.0). Our case highlights the hypercoagulable state associated with COVID-19 disease and the absence of standardised approaches to anticoagulation treatment for this population.

摘要

我们报告了 1 例 38 岁男性患者，该患者患有慢性血栓栓塞性肺动脉高压，正在接受抗凝治疗，近期因 COVID-19 住院，尽管华法林（国际标准化比值（INR）为 3.0）进行了治疗性抗凝治疗，但仍反复发作急性肺栓塞。我们的病例突出了 COVID-19 疾病相关的高凝状态，以及缺乏针对该人群的抗凝治疗标准方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c2a/7844927/1093d27012ba/bcr-2020-238733f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c2a/7844927/336734c56bee/bcr-2020-238733f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c2a/7844927/c7ac9d29128e/bcr-2020-238733f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c2a/7844927/1093d27012ba/bcr-2020-238733f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c2a/7844927/336734c56bee/bcr-2020-238733f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c2a/7844927/c7ac9d29128e/bcr-2020-238733f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c2a/7844927/1093d27012ba/bcr-2020-238733f03.jpg

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Scientific and Standardization Committee communication: Clinical guidance on the diagnosis, prevention, and treatment of venous thromboembolism in hospitalized patients with COVID-19.科学与标准化委员会通讯：新型冠状病毒肺炎住院患者静脉血栓栓塞症诊断、预防及治疗的临床指南
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Venous thromboembolism in COVID-19 patients.
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Eur Respir Rev. 2022 Mar 9;31(163). doi: 10.1183/16000617.0185-2021. Print 2022 Mar 31.
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