氢化 TiO 纳米管/钛箔复合材料的可见光诱导抗菌和促成骨细胞增殖性能。

Visible light-induced antibacterial and osteogenic cell proliferation properties of hydrogenated TiO nanotubes/Ti foil composite.

机构信息

Laboratory of Biomaterials and Biomechanics, School of Stomatology, Capital Medical University, Beijing 100050, People's Republic of China.

Beijing Key Laboratory of Tooth Regeneration and Function Reconstruction, School of Stomatology, Capital Medical University, Beijing 100050, People's Republic of China.

出版信息

Nanotechnology. 2021 May 7;32(19):195101. doi: 10.1088/1361-6528/abe156.

DOI:10.1088/1361-6528/abe156

PMID:33513586

Abstract

We successfully fabricated the hydrogenated TiO nanotubes/Ti foil (H-TNTs/f-Ti) composite via one-step anodization and two-step annealing. H-TNTs/f-Ti composite had a higher visible light-induced photoelectric response and more hydroxyl functional groups compared with Ti foil and unmodified TiO nanotubes/Ti foil composite, which contributed to limiting the proliferation of Streptococcus mutans and Porphyromonas gingivalis, promoting the proliferation of MC3T3-E1 cell on the hydroxylated surface, and improving the biocompatibility with osteogenic cells. Our study provides a simple and effective method for significantly improving dental implant efficacy.

摘要

我们通过一步阳极氧化和两步退火成功制备了氢化 TiO 纳米管/钛箔（H-TNTs/f-Ti）复合材料。与钛箔和未经修饰的 TiO 纳米管/钛箔复合材料相比，H-TNTs/f-Ti 复合材料具有更高的可见光诱导光电响应和更多的羟基官能团，这有助于限制变形链球菌和牙龈卟啉单胞菌的增殖，促进 MC3T3-E1 细胞在羟基化表面上的增殖，并提高与成骨细胞的生物相容性。我们的研究为显著提高牙种植体的疗效提供了一种简单有效的方法。