COVID-19：从受孕到出生的不确定性。
COVID-19: Uncertainties from Conception to Birth.
机构信息
Hospital Sírio-Libanês, Brasília, DF, Brazil.
Maternidade Climério de Oliveira, Universidade Federal da Bahia, Salvador, BA, Brazil.
出版信息
Rev Bras Ginecol Obstet. 2021 Jan;43(1):54-60. doi: 10.1055/s-0040-1721856. Epub 2021 Jan 29.
Abstract
Scientific information on the impact of the new coronavirus (SARS-CoV-2) on the health of pregnant women, fetuses and newborns is considered of limited confidence, lacking good-quality evidence, and drawing biased conclusions. As a matter of fact, the initial impressions that the evolution of COVID-19 was no different between pregnant and non-pregnant women, and that SARS-CoV-2 was not vertically transmitted, are confronted by the documentation of worsening of the disease during pregnancy, poor obstetric outcomes, and the possibility of vertical transmission. The present article aims to compile the data available on the association of COVID-19 and reproductive events, from conception to birth.
摘要
关于新型冠状病毒（SARS-CoV-2）对孕妇、胎儿和新生儿健康影响的科学信息被认为可信度有限，缺乏高质量的证据，并得出有偏差的结论。事实上，最初的印象是 COVID-19 在孕妇和非孕妇中的演变没有区别，而且 SARS-CoV-2 不会垂直传播，但随后有文献记录表明，妊娠期间疾病恶化、产科结局不良以及垂直传播的可能性。本文旨在汇编从受孕到分娩与 COVID-19 和生殖事件相关的现有数据。
相似文献
1
COVID-19: Uncertainties from Conception to Birth.COVID-19：从受孕到出生的不确定性。
Rev Bras Ginecol Obstet. 2021 Jan;43(1):54-60. doi: 10.1055/s-0040-1721856. Epub 2021 Jan 29.
2
An Analysis of 38 Pregnant Women With COVID-19, Their Newborn Infants, and Maternal-Fetal Transmission of SARS-CoV-2: Maternal Coronavirus Infections and Pregnancy Outcomes.分析 38 例 COVID-19 孕妇、其新生儿和 SARS-CoV-2 的母婴传播：冠状病毒感染与妊娠结局。
Arch Pathol Lab Med. 2020 Jul 1;144(7):799-805. doi: 10.5858/arpa.2020-0901-SA.
3
Delivery in pregnant women infected with SARS-CoV-2: A fast review.孕妇感染 SARS-CoV-2 的分娩：快速综述。
Int J Gynaecol Obstet. 2020 Jul;150(1):41-46. doi: 10.1002/ijgo.13166. Epub 2020 May 1.
4
SARS-CoV-2 in pregnancy: characteristics and outcomes of hospitalized and non-hospitalized women due to COVID-19.SARS-CoV-2 在妊娠中的表现：因 COVID-19 住院和未住院的女性的特征和结局。
J Matern Fetal Neonatal Med. 2022 Jul;35(14):2648-2654. doi: 10.1080/14767058.2020.1793320. Epub 2020 Jul 20.
5
COVID-19 infection in pregnant women, preterm delivery, birth weight, and vertical transmission: a systematic review and meta-analysis.COVID-19 感染与孕妇、早产、出生体重和垂直传播：系统评价和荟萃分析。
Cad Saude Publica. 2020;36(7):e00087320. doi: 10.1590/0102-311x00087320. Epub 2020 Jul 17.
6
Potential effects of SARS-CoV-2 infection during pregnancy on fetuses and newborns are worthy of attention.孕期感染新型冠状病毒对胎儿和新生儿的潜在影响值得关注。
J Obstet Gynaecol Res. 2020 Oct;46(10):1951-1957. doi: 10.1111/jog.14406. Epub 2020 Aug 10.
7
Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis.妊娠期冠状病毒谱感染（SARS、MERS、COVID-19）结局的系统评价和荟萃分析。
Am J Obstet Gynecol MFM. 2020 May;2(2):100107. doi: 10.1016/j.ajogmf.2020.100107. Epub 2020 Mar 25.
8
A Review on Mode of Delivery during COVID-19 between December 2019 and April 2020.2019 年 12 月至 2020 年 4 月期间 COVID-19 期间的分娩方式综述。
Am J Perinatol. 2021 Mar;38(4):332-341. doi: 10.1055/s-0040-1721658. Epub 2020 Dec 7.
9
Coronavirus disease 2019 (COVID-19) pandemic and pregnancy.2019 冠状病毒病（COVID-19）大流行与妊娠。
Am J Obstet Gynecol. 2020 Jun;222(6):521-531. doi: 10.1016/j.ajog.2020.03.021. Epub 2020 Mar 23.
10
Neonatal Late Onset Infection with Severe Acute Respiratory Syndrome Coronavirus 2.新生儿严重急性呼吸综合征冠状病毒 2 型晚发感染。
Am J Perinatol. 2020 Jun;37(8):869-872. doi: 10.1055/s-0040-1710541. Epub 2020 May 2.
引用本文的文献
1
Breastfeeding media coverage and beliefs during the COVID-19 pandemic in Mexico: implications for breastfeeding equity.墨西哥 COVID-19 大流行期间的母乳喂养媒体报道和观念：对母乳喂养公平性的影响。
Int J Equity Health. 2021 Dec 20;20(1):260. doi: 10.1186/s12939-021-01588-y.
2
Dyspnea and COVID-19: A Review of Confounding Diagnoses during the Postpartum Period.呼吸困难与 COVID-19：产后期间混淆性诊断的综述。
Rev Bras Ginecol Obstet. 2021 Nov;43(11):862-869. doi: 10.1055/s-0041-1736304. Epub 2021 Dec 6.
3
Risk factors for severe COVID-19 infection in Brazilian children.巴西儿童重症 COVID-19 感染的危险因素。
Braz J Infect Dis. 2021 Nov-Dec;25(6):101650. doi: 10.1016/j.bjid.2021.101650. Epub 2021 Nov 10.
4
Breastfeeding Media Coverage and Beliefs During the COVID-19 Pandemic in Mexico: Implications for Breastfeeding Equity.墨西哥新冠疫情期间母乳喂养的媒体报道与观念：对母乳喂养公平性的影响
Res Sq. 2021 May 19:rs.3.rs-528093. doi: 10.21203/rs.3.rs-528093/v1.
本文引用的文献
1
ACE2 Expression in Kidney and Testis May Cause Kidney and Testis Infection in COVID-19 Patients.血管紧张素转换酶2（ACE2）在肾脏和睾丸中的表达可能导致COVID-19患者的肾脏和睾丸感染。
Front Med (Lausanne). 2021 Jan 13;7:563893. doi: 10.3389/fmed.2020.563893. eCollection 2020.
2
The SARS-CoV-2 receptor, angiotensin-converting enzyme 2, is required for human endometrial stromal cell decidualization†.SARS-CoV-2 受体血管紧张素转换酶 2 是人类子宫内膜基质细胞蜕膜化所必需的†。
Biol Reprod. 2021 Feb 11;104(2):336-343. doi: 10.1093/biolre/ioaa211.
3
Unprecedented reduction in births of very low birthweight (VLBW) and extremely low birthweight (ELBW) infants during the COVID-19 lockdown in Ireland: a 'natural experiment' allowing analysis of data from the prior two decades.在爱尔兰 COVID-19 封锁期间，极低出生体重（VLBW）和超低出生体重（ELBW）婴儿的出生数量出现前所未有的下降：这是一项“自然实验”，可以分析过去二十年的相关数据。
BMJ Glob Health. 2020 Sep;5(9). doi: 10.1136/bmjgh-2020-003075.
4
Clinical characteristics and risk factors for mortality in obstetric patients with severe COVID-19 in Brazil: a surveillance database analysis.巴西产科重症 COVID-19 患者的临床特征和死亡风险因素：监测数据库分析。
BJOG. 2020 Dec;127(13):1618-1626. doi: 10.1111/1471-0528.16470. Epub 2020 Sep 14.
5
Inclusion of pregnant women in COVID-19 vaccine development.将孕妇纳入新冠病毒疫苗研发。
Lancet Infect Dis. 2020 Sep;20(9):1007-1008. doi: 10.1016/S1473-3099(20)30638-1. Epub 2020 Aug 11.
6
Danish premature birth rates during the COVID-19 lockdown.丹麦 COVID-19 封锁期间的早产率。
Arch Dis Child Fetal Neonatal Ed. 2021 Jan;106(1):93-95. doi: 10.1136/archdischild-2020-319990. Epub 2020 Aug 11.
7
SARS-CoV-2 and human reproduction: An open question.严重急性呼吸综合征冠状病毒2（SARS-CoV-2）与人类生殖：一个悬而未决的问题。
EClinicalMedicine. 2020 Jul 24;25:100473. doi: 10.1016/j.eclinm.2020.100473. eCollection 2020 Aug.
8
Maternal COVID-19 infection, clinical characteristics, pregnancy, and neonatal outcome: A prospective cohort study.母亲感染 COVID-19、临床特征、妊娠和新生儿结局：一项前瞻性队列研究。
Eur J Obstet Gynecol Reprod Biol. 2020 Sep;252:559-562. doi: 10.1016/j.ejogrb.2020.07.008. Epub 2020 Jul 15.
9
Fetal deaths in pregnancies with SARS-CoV-2 infection in Brazil: A case series.巴西感染严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）的妊娠中的死胎：病例系列
Case Rep Womens Health. 2020 Jul 12;27:e00243. doi: 10.1016/j.crwh.2020.e00243. eCollection 2020 Jul.
10
Clinical management of coronavirus disease 2019 (COVID-19) in pregnancy: recommendations of WAPM-World Association of Perinatal Medicine.《世界围产医学会关于妊娠期 2019 年冠状病毒病（COVID-19）的临床管理：建议》。
J Perinat Med. 2020 Nov 26;48(9):857-866. doi: 10.1515/jpm-2020-0265.
Zotero 插件