Department of Obstetrics and Gynecology, Faculdade de Ciências Médicas da Universidade de Campinas, Campinas, SP, Brazil.
Department of Gynecology and Obstetrics, Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Rev Bras Ginecol Obstet. 2021 Jan;43(1):66-71. doi: 10.1055/s-0040-1721351. Epub 2021 Jan 29.
Uterine leiomyoma is the most prevalent benign type of gynecological tumor. It affects more than 80% of women worldwide and, within this group, more than 50% may be asymptomatic. However, large fibroid volumes may be associated with symptoms of extrinsic compression, and most of the cases do not present atypical cells. We present the case of a 49-year-old woman who underwent a total abdominal hysterectomy of a 13.5-kg uterine leiomyoma with no malignancies at histopathology and review the literature about giant uterine leiomyomas and their clinical repercussion. We concluded that large volumes do not always pose a threat regarding malignancy; however, future molecular studies are needed to investigate giant uterine fibroids.
子宫肌瘤是最常见的妇科良性肿瘤。它影响全球超过 80%的女性，而在这一组中，超过 50%可能无症状。然而，大的肌瘤体积可能与外在压迫的症状相关，并且大多数病例没有不典型细胞。我们报告了一例 49 岁女性，她接受了全子宫切除术，切除了一个 13.5 公斤的子宫肌瘤，组织病理学无恶性肿瘤，并回顾了关于巨大子宫肌瘤及其临床影响的文献。我们得出结论，大体积并不总是存在恶性肿瘤的威胁；然而，需要进一步的分子研究来探讨巨大的子宫肌瘤。
