甲状腺切除术后的慢性疲劳：一项以患者为中心的调查。
Chronic Fatigue After Thyroidectomy: A Patient-Centered Survey.
作者信息
Lumpkin Stephanie T, Button Julia, Stratton Lee, Strassle Paula D, Kim Lawrence T
机构信息
Department of Surgery, 2332University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Department of Surgery, 2462University of Chicago, Chicago, IL, USA.
出版信息
Am Surg. 2022 Feb;88(2):260-266. doi: 10.1177/0003134821989054. Epub 2021 Jan 31.
BACKGROUND
Fatigue after thyroidectomy is common, but there is a paucity of data regarding its prevalence and duration. We hypothesized that total thyroidectomy (TT) patients would have more long-term fatigue than thyroid lobectomy (TL) patients.
METHODS
Statewide survey of thyroidectomy patients (2004-2017) was carried out.
RESULTS
281 patients completed the survey. 216 respondents (77%) had TT and 65 (23%) had TL. Within one year of surgery, 172 (61%) respondents recalled being troubled by new fatigue all, most, or some of the time. Total thyroidectomy patients were more likely to report new fatigue (69% vs. 44%, aOR 2.72, 95% CI 1.44 to 5.18). Of patients ( = 172) reporting new fatigue, 67 (39%) reported at least moderate improvement. Nineteen (28%) saw improvement within 1 year, 35 (52%) saw improvement in 1-2 years, and 11 (16%) saw improvement after 2 years.
CONCLUSION
Long-term fatigue after TT can be debilitating, long-lasting, and less prevalent after TL.
背景
甲状腺切除术后疲劳很常见，但关于其发生率和持续时间的数据却很少。我们推测全甲状腺切除术（TT）患者比甲状腺叶切除术（TL）患者更容易出现长期疲劳。
方法
对全州范围内的甲状腺切除患者（2004 - 2017年）进行了调查。
结果
281名患者完成了调查。216名受访者（77%）接受了全甲状腺切除术，65名（23%）接受了甲状腺叶切除术。在术后一年内，172名（61%）受访者回忆说自己一直、大部分或有时会受到新出现的疲劳困扰。全甲状腺切除术患者更有可能报告出现新的疲劳（69%对44%，调整后比值比为2.72，95%置信区间为1.44至5.18）。在报告有新疲劳的患者（n = 172）中，67名（39%）报告至少有中度改善。19名（28%）在1年内有所改善，35名（52%）在1至2年内有所改善，11名（16%）在2年后有所改善。
结论
全甲状腺切除术后的长期疲劳可能使人虚弱、持续时间长，而在甲状腺叶切除术后则不太常见。
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