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多囊卵巢综合征的诊断：何时及如何使用哪些标准？

Diagnosis of Polycystic Ovary Syndrome: Which Criteria to Use and When?

机构信息

Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology, Zucker School of Medicine at Hofstra/Northwell, 210A E 64th St. 1st Floor, New York, NY 10065, USA.

Department of Medicine, Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, Atran Building, 1428 Madison Avenue, 4th Floor, Room 4-36, New York, NY 10029, USA.

出版信息

Endocrinol Metab Clin North Am. 2021 Mar;50(1):11-23. doi: 10.1016/j.ecl.2020.10.002.

DOI:10.1016/j.ecl.2020.10.002
PMID:33518179
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7860982/
Abstract

Current diagnostic criteria for polycystic ovary syndrome (PCOS) are based on expert opinion. This article reviews the rationale for and the limitations of these criteria as well as which criteria to use and when. The insights provided into PCOS pathogenesis by modern genetic analyses and the promise of objective data mining approaches for biologically relevant disease classification are discussed.

摘要

多囊卵巢综合征（PCOS）的现行诊断标准基于专家意见。本文回顾了这些标准的原理和局限性，以及何时使用哪些标准。本文还讨论了现代遗传分析为 PCOS 发病机制提供的见解，以及客观数据挖掘方法在生物学相关疾病分类方面的应用前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd8a/7860982/5ffebece45eb/nihms-1661672-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd8a/7860982/1a6552fd6ff9/nihms-1661672-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd8a/7860982/5ffebece45eb/nihms-1661672-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd8a/7860982/1a6552fd6ff9/nihms-1661672-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd8a/7860982/5ffebece45eb/nihms-1661672-f0002.jpg

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Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis.具有新型遗传关联的多囊卵巢综合征的不同亚型：一种无监督的、表型聚类分析。
PLoS Med. 2020 Jun 23;17(6):e1003132. doi: 10.1371/journal.pmed.1003132. eCollection 2020 Jun.
2
Genome-Wide Association Studies.全基因组关联研究
JAMA. 2019 Nov 5;322(17):1705-1706. doi: 10.1001/jama.2019.16479.
3
Screening and Management of the Hyperandrogenic Adolescent: ACOG Committee Opinion, Number 789.青春期高雄激素血症的筛查和管理：ACOG 委员会意见，第 789 号。
达英-35与苍附导痰丸联合使用可有效改善多囊卵巢综合征（PCOS）患者的炎症反应、应激状态和激素水平，显著提高临床治疗效果。
Int J Womens Health. 2025 Jul 29;17:2353-2364. doi: 10.2147/IJWH.S526092. eCollection 2025.
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Redox Biol. 2025 Jul 17;85:103776. doi: 10.1016/j.redox.2025.103776.
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miR-28: A Tiny Player in Cancer Progression and Other Human Diseases.微小RNA-28：癌症进展及其他人类疾病中的小角色
Biomolecules. 2025 May 24;15(6):757. doi: 10.3390/biom15060757.
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