Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN.
Department of Biostatistics, Vanderbilt University, Nashville, TN.
Ethn Dis. 2021 Jan 21;31(1):9-22. doi: 10.18865/ed.31.1.9. eCollection 2021 Winter.
To compare patient-reported social determinants of health (SDOH) to the Brokamp Area Deprivation Index (ADI), and evaluate the association of patient-reported SDOH and ADI with mortality in patients with cardiovascular disease (CVD).
Prospective cohort.
Academic medical center.
Adults with acute coronary syndrome (ACS) and/or acute exacerbation of heart failure (HF) hospitalized between 2011 and 2015.
Patient-reported SDOH included: income range, education, health insurance, and household size. ADI was calculated using census tract level variables of poverty, median income, high school completion, lack of health insurance, assisted income, and vacant housing.
All-cause mortality, up to 5 years follow-up.
The sample was 60% male, 84% White, and 93% insured; mean patient-reported household income was $48,000 (SD $34,000). ADI components were significantly associated with corresponding patient-reported variables. In age, sex, and race adjusted Cox regression models, ADI was associated with mortality for ACS (HR 1.23, 95% CI 1.06, 1.42), but not HF (HR 1.09, 95% CI .99, 1.21). Mortality models for ACS improved with consideration of social determinants data (C-statistics: base demographic model=.612; ADI added=.644; patient-reported SDOH added=.675; both ADI and patient-reported SDOH added=.689). HF mortality models improved only slightly (C-statistics: .600, .602, .617, .620, respectively).
The Brokamp ADI is associated with mortality in hospitalized patients with CVD. In the absence of available patient-reported data, hospitals could implement the Brokamp ADI as an approximation for patient-reported data to enhance risk stratification of patients with CVD.
比较患者报告的健康社会决定因素(SDOH)与布罗坎普区域剥夺指数(ADI),并评估患者报告的 SDOH 和 ADI 与心血管疾病(CVD)患者死亡率的关系。
前瞻性队列研究。
学术医疗中心。
2011 年至 2015 年间因急性冠状动脉综合征(ACS)和/或心力衰竭急性加重而住院的成年人。
患者报告的 SDOH 包括:收入范围、教育程度、医疗保险和家庭规模。ADI 是通过贫困、中位数收入、高中完成率、缺乏医疗保险、援助收入和空置住房等普查区水平变量计算得出的。
全因死亡率,随访时间长达 5 年。
样本中 60%为男性,84%为白人,93%有保险;患者报告的家庭平均收入为 48000 美元(标准差为 34000 美元)。ADI 成分与相应的患者报告变量显著相关。在年龄、性别和种族调整的 Cox 回归模型中,ADI 与 ACS 的死亡率相关(HR 1.23,95%CI 1.06,1.42),但与 HF 无关(HR 1.09,95%CI.99,1.21)。考虑到社会决定因素数据,ACS 的死亡率模型得到了改善(C 统计量:基础人口统计学模型=0.612;ADI 增加=0.644;患者报告的 SDOH 增加=0.675;ADI 和患者报告的 SDOH 均增加=0.689)。HF 死亡率模型仅略有改善(C 统计量:分别为 0.600、0.602、0.617、0.620)。
布罗坎普 ADI 与住院 CVD 患者的死亡率相关。在缺乏可用的患者报告数据的情况下,医院可以实施布罗坎普 ADI 作为患者报告数据的近似值,以增强 CVD 患者的风险分层。