Al-Jindan Reem, Al-Eraky Doaa M
Department of Microbiology and Immunology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Department of Biomedical Dental Science, Division of Microbiology and Immunology, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Saudi J Med Med Sci. 2021 Jan-Apr;9(1):71-74. doi: 10.4103/sjmms.sjmms_449_19. Epub 2020 Dec 15.
is an opportunistic multidrug-resistant pathogen that was first isolated in 2009 and has since been reported from about 30 countries. In Saudi Arabia, only four cases of have previously been reported; here, we report two new cases of this infection. Both patients were polymorbid and had long hospitalization periods with recurrent intensive care unit (ICU) admissions. The findings of the tissue/blood cultures and antimicrobial therapy protocols are explained in the case report. Urine culture in both cases was positive for , and the colonies grew well at 42°C. The fungal isolates were confirmed by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. The first patient was treated with the recommended dose of caspofungin, but he passed away. The second patient was also planned to be treated with caspofungin, but he passed away before the treatment could be initiated. The present cases further corroborate signs of a growing number of reports of in patients with high-risk factors, such as hospitalization in ICU, multiple chronic conditions and prolonged antimicrobial treatment exposure. It also highlights the need for hospitals to further improve their infection control practices to prevent nosocomial infections such as .
是一种机会性多重耐药病原体，于2009年首次分离出来，此后在约30个国家有报道。在沙特阿拉伯，此前仅报告过4例；在此，我们报告两例这种感染的新病例。两名患者都患有多种疾病，住院时间长，多次入住重症监护病房（ICU）。病例报告中解释了组织/血液培养结果和抗菌治疗方案。两例患者的尿液培养均对 呈阳性，菌落在42°C生长良好。真菌分离株通过基质辅助激光解吸电离飞行时间质谱法进行确认。第一名患者接受了推荐剂量的卡泊芬净治疗，但去世了。第二名患者也计划接受卡泊芬净治疗，但在治疗开始前去世了。目前的病例进一步证实了有越来越多关于具有高危因素患者感染 的报道迹象，如入住ICU、患有多种慢性病和长期接触抗菌治疗。这也凸显了医院进一步改善感染控制措施以预防诸如 等医院感染的必要性。
