亚洲医疗机构流行病学综述
: A Mini Review on Epidemiology in Healthcare Facilities in Asia.
作者信息
Thatchanamoorthy Nishanthinie, Rukumani Devi Velayuthan, Chandramathi Samudi, Tay Sun Tee
机构信息
Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Jalan Profesor Diraja Ungku Aziz, Kuala Lumpur 50603, Wilayah Persekutuan, Malaysia.
Department of Medical Microbiology, University Malaya Medical Centre, Jalan Profesor Diraja Ungku Aziz, Kuala Lumpur 59100, Wilayah Persekutuan, Malaysia.
出版信息
J Fungi (Basel). 2022 Oct 26;8(11):1126. doi: 10.3390/jof8111126.
a newly emerging healthcare-associated yeast pathogen from the Metschnikowiaceae family, was first described in the ear canal of an elderly Japanese patient in 2009. The yeast is one of the causative agents of candidemia, which has been linked with nosocomial outbreaks and high mortality rates in healthcare facilities worldwide. Since its first isolation, the occurrence of in six continents has becomes a grave concern for the healthcare professionals and scientific community. Recent reports showed the identification of five geographically distinct clades and high rates of antifungal resistance associated with . Till date, there are no effective treatment options, and standardized measures for prevention and control of infection in healthcare facilities. This leads to frequent therapeutic failures and complicates the eradication of infection in healthcare facilities. Thus, this review focuses on the recent understanding of the epidemiology, risk factors, diagnosis, transmission and prevention and control strategies of infection in healthcare facilities in Asia.
一种新出现的来自梅奇尼科夫酵母科的医疗保健相关酵母病原体，于2009年首次在一名老年日本患者的耳道中被发现。这种酵母是念珠菌血症的病原体之一，与全球医疗机构中的医院感染暴发和高死亡率有关。自首次分离以来，它在六大洲的出现已成为医疗保健专业人员和科学界严重关切的问题。最近的报告显示，已鉴定出五个地理上不同的进化枝，并且与该病原体相关的抗真菌耐药率很高。迄今为止，尚无有效的治疗选择，也没有医疗机构中预防和控制该病原体感染的标准化措施。这导致频繁的治疗失败，并使医疗机构中该病原体感染的根除复杂化。因此，本综述重点关注亚洲医疗机构中对该病原体感染的流行病学、危险因素、诊断、传播以及预防和控制策略的最新认识。
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