• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

调节女性睡眠的神经生物学和激素机制

Neurobiological and Hormonal Mechanisms Regulating Women's Sleep.

作者信息

Dorsey Alanna, de Lecea Luis, Jennings Kimberly J

机构信息

Department of Psychiatry and Behavioral Sciences, School of Medicine, Stanford University, Stanford, CA, United States.

出版信息

Front Neurosci. 2021 Jan 14;14:625397. doi: 10.3389/fnins.2020.625397. eCollection 2020.

DOI:10.3389/fnins.2020.625397
PMID:33519372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7840832/
Abstract

Sleep is crucial for optimal well-being, and sex differences in sleep quality have significant implications for women's health. We review the current literature on sex differences in sleep, such as differences in objective and subjective sleep measures and their relationship with aging. We then discuss the convincing evidence for the role of ovarian hormones in regulating female sleep, and survey how these hormones act on a multitude of brain regions and neurochemicals to impact sleep. Lastly, we identify several important areas in need of future research to narrow the knowledge gap and improve the health of women and other understudied populations.

摘要

睡眠对于最佳健康状态至关重要,睡眠质量的性别差异对女性健康具有重大影响。我们回顾了当前关于睡眠性别差异的文献,例如客观和主观睡眠测量方面的差异及其与衰老的关系。然后我们讨论了卵巢激素在调节女性睡眠中作用的有力证据,并探究这些激素如何作用于多个脑区和神经化学物质以影响睡眠。最后,我们确定了几个未来研究需要关注的重要领域,以缩小知识差距并改善女性及其他研究较少人群的健康状况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64b/7840832/a6f629c8868c/fnins-14-625397-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64b/7840832/a63eca377a02/fnins-14-625397-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64b/7840832/b5f66498142d/fnins-14-625397-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64b/7840832/a6f629c8868c/fnins-14-625397-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64b/7840832/a63eca377a02/fnins-14-625397-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64b/7840832/b5f66498142d/fnins-14-625397-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d64b/7840832/a6f629c8868c/fnins-14-625397-g003.jpg

相似文献

1
Neurobiological and Hormonal Mechanisms Regulating Women's Sleep.调节女性睡眠的神经生物学和激素机制
Front Neurosci. 2021 Jan 14;14:625397. doi: 10.3389/fnins.2020.625397. eCollection 2020.
2
Exploring sex and gender differences in sleep health: a Society for Women's Health Research Report.探索睡眠健康中的性别差异:女性健康研究协会报告
J Womens Health (Larchmt). 2014 Jul;23(7):553-62. doi: 10.1089/jwh.2014.4816. Epub 2014 Jun 23.
3
Ovarian hormones and obesity.卵巢激素与肥胖
Hum Reprod Update. 2017 May 1;23(3):300-321. doi: 10.1093/humupd/dmw045.
4
Progesterone Is Important for Transgender Women's Therapy-Applying Evidence for the Benefits of Progesterone in Ciswomen.孕激素对跨性别女性治疗至关重要——应用孕激素对 cis 女性有益的证据。
J Clin Endocrinol Metab. 2019 Apr 1;104(4):1181-1186. doi: 10.1210/jc.2018-01777.
5
Endogenous and Exogenous Estrogen Exposures: How Women's Reproductive Health Can Drive Brain Aging and Inform Alzheimer's Prevention.内源性和外源性雌激素暴露:女性生殖健康如何影响大脑衰老及为阿尔茨海默病预防提供依据。
Front Aging Neurosci. 2022 Mar 9;14:831807. doi: 10.3389/fnagi.2022.831807. eCollection 2022.
6
Actigraphic and self-reported sleep quality in women: associations with ovarian hormones and mood.女性的活动记录仪监测睡眠质量与自我报告睡眠质量:与卵巢激素及情绪的关联
Sleep Med. 2015 Oct;16(10):1217-24. doi: 10.1016/j.sleep.2015.06.009. Epub 2015 Jun 26.
7
Steroid Hormones and Their Action in Women's Brains: The Importance of Hormonal Balance.类固醇激素及其在女性大脑中的作用:激素平衡的重要性。
Front Public Health. 2018 May 23;6:141. doi: 10.3389/fpubh.2018.00141. eCollection 2018.
8
The Menstrual Cycle's Influence on Sleep Duration and Cardiovascular Health: A Comprehensive Review.月经周期对睡眠时间和心血管健康的影响:一项综合综述。
Cureus. 2023 Oct 18;15(10):e47292. doi: 10.7759/cureus.47292. eCollection 2023 Oct.
9
The role of ovarian hormones in the pathophysiology of perimenopausal sleep disturbances: A systematic review.卵巢激素在围绝经期睡眠障碍病理生理学中的作用:一项系统综述。
Sleep Med Rev. 2022 Dec;66:101710. doi: 10.1016/j.smrv.2022.101710. Epub 2022 Oct 27.
10
Sleep and menopause.睡眠与更年期
Nurs Clin North Am. 2004 Mar;39(1):97-115. doi: 10.1016/j.cnur.2003.11.006.

引用本文的文献

1
Prevalence and correlates of restless leg syndrome in psychiatric outpatients in Lebanon.黎巴嫩精神科门诊患者中不宁腿综合征的患病率及其相关因素
Sci Rep. 2025 Aug 9;15(1):29128. doi: 10.1038/s41598-025-15036-2.
2
Sleep Across the Lifespan: A Neurobehavioral Perspective.全生命周期的睡眠:神经行为学视角
Curr Sleep Med Rep. 2025;11(1):7. doi: 10.1007/s40675-025-00322-2. Epub 2025 Feb 5.
3
Assessment of Sleep Quality and Its Determinants Among Patients with Type 2 Diabetes Mellitus in Mogadishu, Somalia: A Cross-Sectional Study.

本文引用的文献

1
The mammalian circadian pacemaker regulates wakefulness via CRF neurons in the paraventricular nucleus of the hypothalamus.哺乳动物的昼夜节律起搏器通过下丘脑室旁核中的促肾上腺皮质激素释放因子(CRF)神经元调节清醒状态。
Sci Adv. 2020 Nov 6;6(45). doi: 10.1126/sciadv.abd0384. Print 2020 Nov.
2
Dopamine transporter function fluctuates across sleep/wake state: potential impact for addiction.多巴胺转运体功能在睡眠/清醒状态间波动:对成瘾的潜在影响。
Neuropsychopharmacology. 2021 Mar;46(4):699-708. doi: 10.1038/s41386-020-00879-2. Epub 2020 Oct 8.
3
Gender differences in adolescent sleep neurophysiology: a high-density sleep EEG study.
索马里摩加迪沙2型糖尿病患者睡眠质量及其决定因素的评估:一项横断面研究
Diabetes Metab Syndr Obes. 2025 Jun 15;18:1949-1965. doi: 10.2147/DMSO.S533810. eCollection 2025.
4
Activation of anoctamin-1 calcium-activated chloride channels reduces voluntary alcohol consumption in rats.激活anoctamin-1钙激活氯离子通道可减少大鼠的自愿酒精摄入量。
Neuropharmacology. 2025 Sep 1;275:110498. doi: 10.1016/j.neuropharm.2025.110498. Epub 2025 May 3.
5
Effects of Traumatic Brain Injury on the Orexin/Hypocretin System.创伤性脑损伤对食欲素/下丘脑泌素系统的影响。
Neurotrauma Rep. 2025 Apr 21;6(1):322-335. doi: 10.1089/neur.2024.0111. eCollection 2025.
6
Association between sleep duration and patterns and obesity: a cross-sectional study of the 2007-2018 national health and nutrition examination survey.睡眠时间及模式与肥胖之间的关联:一项基于2007 - 2018年国家健康与营养检查调查的横断面研究
BMC Public Health. 2025 Apr 21;25(1):1460. doi: 10.1186/s12889-025-22433-9.
7
Multidimensional Sleep and Self-Rated Physical Health and Depressive Symptoms Among Retired Older Adults: A Sex-Stratified Analysis.退休老年人的多维睡眠、自评身体健康与抑郁症状:一项性别分层分析
Behav Sleep Med. 2025 Jul-Aug;23(4):540-551. doi: 10.1080/15402002.2025.2493651. Epub 2025 Apr 17.
8
Different temporal relationship between sex hormones and sleep status in midlife women: a longitudinal cohort study.中年女性性激素与睡眠状态的不同时间关系:一项纵向队列研究。
Sex Med. 2025 Mar 2;13(1):qfaf009. doi: 10.1093/sexmed/qfaf009. eCollection 2025 Feb.
9
Sex differences in reward-based operant conditioning performance and neurotransmitter changes following chronic sleep restriction stress in rats.大鼠慢性睡眠限制应激后基于奖励的操作性条件反射行为表现及神经递质变化的性别差异
Behav Brain Funct. 2025 Feb 28;21(1):3. doi: 10.1186/s12993-025-00268-z.
10
Sleep and Brain Function at Menopause.更年期的睡眠与脑功能
J Midlife Health. 2024 Oct-Dec;15(4):221-224. doi: 10.4103/jmh.jmh_201_24. Epub 2025 Jan 2.
青少年睡眠神经生理学的性别差异:一项高密度睡眠 EEG 研究。
Sci Rep. 2020 Sep 28;10(1):15935. doi: 10.1038/s41598-020-72802-0.
4
Hypothalamic circuitry underlying stress-induced insomnia and peripheral immunosuppression.应激诱导的失眠和外周免疫抑制背后的下丘脑神经回路。
Sci Adv. 2020 Sep 9;6(37). doi: 10.1126/sciadv.abc2590. Print 2020 Sep.
5
Periodic Remodeling in a Neural Circuit Governs Timing of Female Sexual Behavior.神经回路的周期性重塑控制雌性性行为的时间。
Cell. 2019 Nov 27;179(6):1393-1408.e16. doi: 10.1016/j.cell.2019.10.025. Epub 2019 Nov 14.
6
Neuroendocrine Control of Sleep.睡眠的神经内分泌控制
Curr Top Behav Neurosci. 2019;43:353-378. doi: 10.1007/7854_2019_107.
7
The human stress response.人类应激反应。
Nat Rev Endocrinol. 2019 Sep;15(9):525-534. doi: 10.1038/s41574-019-0228-0. Epub 2019 Jun 27.
8
Gonadal hormones differentially regulate sex-specific stress effects on glia in the medial prefrontal cortex.性腺激素差异调节性别特异性应激对前额皮质内侧胶质细胞的影响。
J Neuroendocrinol. 2019 Aug;31(8):e12762. doi: 10.1111/jne.12762. Epub 2019 Jul 15.
9
Sleep spindle characteristics in adolescents.青少年睡眠纺锤波特征。
Clin Neurophysiol. 2019 Jun;130(6):893-902. doi: 10.1016/j.clinph.2019.02.019. Epub 2019 Mar 18.
10
Sex differences in stress reactivity in arousal and attention systems.性别的应激反应在唤醒和注意系统中的差异。
Neuropsychopharmacology. 2019 Jan;44(1):129-139. doi: 10.1038/s41386-018-0137-2. Epub 2018 Jun 29.