Sattler Ross, Ekanayake Lakmal S, Richardson Amber
Medicine, Ohio University Heritage College of Osteopathic Medicine, Athens, USA.
Internal Medicine, Springfield Regional Medical Center, Springfield, USA.
Cureus. 2020 Dec 25;12(12):e12287. doi: 10.7759/cureus.12287.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a single-stranded, positive-sense, enveloped ribonucleic acid (RNA) virus. SARS-CoV-2 and its associated disease coronavirus disease 2019 (COVID-19) has caused a global pandemic in the year 2019-2020. COVID-19 has caused widespread death, economic burden, and overcrowding of hospitals. As of September 2020, there is no reliable pharmacological treatment for patients affected by COVID-19. Herein we present a case of a 41-year-old Caucasian female who presented to the emergency department with flu-like symptoms for the past five days. The patient was admitted for COVID-19 symptoms and subsequently developed COVID-19 associated thrombotic syndrome and ischemic stroke. Below, we discuss risk factors, pathology, and rare manifestations resulting from COVID-19 infection. COVID-19 primarily affects the lungs, but a review of the current literature shows limited cases of ischemic stroke and diffuse thrombosis induced by infection of the novel COVID-19 in relatively healthy individuals with minimal risk factors.
严重急性呼吸综合征冠状病毒2(SARS-CoV-2)是一种单链、正链、包膜核糖核酸(RNA)病毒。SARS-CoV-2及其相关疾病冠状病毒病2019(COVID-19)在2019年至2020年期间引发了全球大流行。COVID-19导致了广泛的死亡、经济负担以及医院人满为患。截至2020年9月,对于感染COVID-19的患者尚无可靠的药物治疗方法。在此,我们报告一例41岁的白种女性病例,该患者在过去五天出现类似流感的症状后前往急诊科就诊。该患者因COVID-19症状入院,随后发展为COVID-19相关血栓形成综合征和缺血性中风。以下,我们将讨论COVID-19感染导致的危险因素、病理以及罕见表现。COVID-19主要影响肺部,但对当前文献的综述显示,在具有最小风险因素的相对健康个体中,由新型COVID-19感染引起的缺血性中风和弥漫性血栓形成的病例有限。