Metformin: an inexpensive and effective treatment in people with diabetes and COVID-19?
作者信息
Dardano Angela, Del Prato Stefano
机构信息
Department of Clinical & Experimental Medicine, University of Pisa, Pisa 56124, Italy.
出版信息
Lancet Healthy Longev. 2021 Jan;2(1):e6-e7. doi: 10.1016/S2666-7568(20)30047-7. Epub 2020 Dec 3.
Abstract
摘要
相似文献
1
Metformin: an inexpensive and effective treatment in people with diabetes and COVID-19?二甲双胍：糖尿病合并新冠肺炎患者的一种廉价且有效的治疗方法？
Lancet Healthy Longev. 2021 Jan;2(1):e6-e7. doi: 10.1016/S2666-7568(20)30047-7. Epub 2020 Dec 3.
2
The Efficacy and Potential Mechanisms of Metformin in the Treatment of COVID-19 in the Diabetics: A Systematic Review.二甲双胍治疗糖尿病合并 COVID-19 的疗效及潜在机制：系统评价。
Front Endocrinol (Lausanne). 2021 Mar 19;12:645194. doi: 10.3389/fendo.2021.645194. eCollection 2021.
3
Metformin lowers lipoprotein(a) levels.
Diabetes Care. 1998 Nov;21(11):2028. doi: 10.2337/diacare.21.11.2028b.
4
Changing incident diabetes regimens: a Veterans Administration cohort study from 2000 to 2005.改变糖尿病治疗方案：一项2000年至2005年退伍军人管理局队列研究。
Diabetes Care. 2007 Aug;30(8):e85. doi: 10.2337/dc07-0650.
5
Metformin is associated with favorable outcomes in patients with COVID-19 and type 2 diabetes mellitus.二甲双胍与 COVID-19 合并 2 型糖尿病患者的良好结局相关。
Sci Rep. 2022 Apr 1;12(1):5553. doi: 10.1038/s41598-022-09639-2.
6
Metformin use in patients hospitalized with COVID-19: lower inflammation, oxidative stress, and thrombotic risk markers and better clinical outcomes.COVID-19 住院患者使用二甲双胍：降低炎症、氧化应激和血栓形成风险标志物，改善临床结局。
J Thromb Thrombolysis. 2022 Feb;53(2):363-371. doi: 10.1007/s11239-022-02631-7. Epub 2022 Jan 18.
7
Metformin does not improve survival of cholangiocarcinoma patients with diabetes.二甲双胍不能提高胆管癌合并糖尿病患者的生存率。
Hepatology. 2016 Feb;63(2):667-8. doi: 10.1002/hep.27821. Epub 2015 May 7.
8
Predictors of adverse in-hospital outcome and recovery in patients with diabetes mellitus and COVID-19 pneumonia in Iraq.伊拉克 COVID-19 肺炎合并糖尿病患者住院不良结局和恢复的预测因素。
Diabetes Metab Syndr. 2021 Jan-Feb;15(1):33-38. doi: 10.1016/j.dsx.2020.12.014. Epub 2020 Dec 5.
9
Metformin use is associated with a decrease in the risk of hospitalization and mortality in COVID-19 patients with diabetes: A population-based study in Lombardy.二甲双胍的使用与 COVID-19 合并糖尿病患者住院和死亡风险的降低相关：伦巴第地区的一项基于人群的研究。
Diabetes Obes Metab. 2022 May;24(5):891-898. doi: 10.1111/dom.14648. Epub 2022 Jan 25.
10
Metformin and pancreatic cancer: a clue requiring investigation.二甲双胍与胰腺癌：有待探究的线索。
Clin Cancer Res. 2012 May 15;18(10):2723-5. doi: 10.1158/1078-0432.CCR-12-0694. Epub 2012 Mar 31.
引用本文的文献
1
Metformin-Induced Apoptosis Is Mediated Through Mitochondrial VDAC1.二甲双胍诱导的细胞凋亡是通过线粒体电压依赖性阴离子通道1介导的。
Pharmaceuticals (Basel). 2025 May 20;18(5):757. doi: 10.3390/ph18050757.
2
Poly(2-Hydroxyethyl Methacrylate) Hydrogel-Based Microneedles for Metformin Release.用于二甲双胍释放的聚甲基丙烯酸2-羟乙酯水凝胶基微针
Glob Chall. 2023 Jul 5;7(8):2300002. doi: 10.1002/gch2.202300002. eCollection 2023 Aug.
3
Triple jeopardy in ageing: COVID-19, co-morbidities and inflamm-ageing.衰老三重困境：COVID-19、合并症和炎症衰老。
Ageing Res Rev. 2022 Jan;73:101494. doi: 10.1016/j.arr.2021.101494. Epub 2021 Oct 22.
4
Adverse Effects of Metformin From Diabetes to COVID-19, Cancer, Neurodegenerative Diseases, and Aging: Is VDAC1 a Common Target?二甲双胍的不良反应：从糖尿病到新冠病毒病、癌症、神经退行性疾病及衰老——电压依赖性阴离子通道1是共同靶点吗？
Front Physiol. 2021 Oct 4;12:730048. doi: 10.3389/fphys.2021.730048. eCollection 2021.
5
The management of type 2 diabetes before, during and after Covid-19 infection: what is the evidence?新冠病毒感染前后 2 型糖尿病的管理：有哪些证据？
Cardiovasc Diabetol. 2021 Oct 1;20(1):198. doi: 10.1186/s12933-021-01389-1.
6
Drug delivery systems as immunomodulators for therapy of infectious disease: Relevance to COVID-19.药物传递系统作为治疗传染病的免疫调节剂：与 COVID-19 的相关性。
Adv Drug Deliv Rev. 2021 Nov;178:113848. doi: 10.1016/j.addr.2021.113848. Epub 2021 Jun 25.
本文引用的文献
1
Metformin and risk of mortality in patients hospitalised with COVID-19: a retrospective cohort analysis.二甲双胍治疗 COVID-19 住院患者的死亡率风险：一项回顾性队列分析。
Lancet Healthy Longev. 2021 Jan;2(1):e34-e41. doi: 10.1016/S2666-7568(20)30033-7. Epub 2020 Dec 3.
2
Metformin Use Is Associated With Reduced Mortality in a Diverse Population With COVID-19 and Diabetes.二甲双胍的使用与 COVID-19 合并糖尿病的多样化患者人群死亡率降低相关。
Front Endocrinol (Lausanne). 2021 Jan 13;11:600439. doi: 10.3389/fendo.2020.600439. eCollection 2020.
3
A geroscience perspective on immune resilience and infectious diseases: a potential case for metformin.衰老科学视角下的免疫弹性与传染病：二甲双胍的潜在案例。
Geroscience. 2021 Jun;43(3):1093-1112. doi: 10.1007/s11357-020-00261-6. Epub 2020 Sep 9.
4
Metformin Is Associated with Higher Incidence of Acidosis, but Not Mortality, in Individuals with COVID-19 and Pre-existing Type 2 Diabetes.二甲双胍与 COVID-19 合并 2 型糖尿病患者酸中毒发生率升高相关，但与死亡率无关。
Cell Metab. 2020 Oct 6;32(4):537-547.e3. doi: 10.1016/j.cmet.2020.08.013. Epub 2020 Aug 20.
5
Hyperglycemia at Hospital Admission Is Associated With Severity of the Prognosis in Patients Hospitalized for COVID-19: The Pisa COVID-19 Study.入院时高血糖与 COVID-19 住院患者预后严重程度相关：比萨 COVID-19 研究。
Diabetes Care. 2020 Oct;43(10):2345-2348. doi: 10.2337/dc20-1380. Epub 2020 Aug 11.
6
COVID-19 in people with diabetes: understanding the reasons for worse outcomes.COVID-19 与糖尿病：了解预后不佳的原因。
Lancet Diabetes Endocrinol. 2020 Sep;8(9):782-792. doi: 10.1016/S2213-8587(20)30238-2. Epub 2020 Jul 17.
7
Metformin Treatment Was Associated with Decreased Mortality in COVID-19 Patients with Diabetes in a Retrospective Analysis.回顾性分析显示，二甲双胍治疗与 COVID-19 合并糖尿病患者的死亡率降低相关。
Am J Trop Med Hyg. 2020 Jul;103(1):69-72. doi: 10.4269/ajtmh.20-0375. Epub 2020 May 21.
8
Clinical Characteristics and Outcomes of Patients With Diabetes and COVID-19 in Association With Glucose-Lowering Medication.患有糖尿病和 COVID-19 患者的临床特征和转归与降糖药物的关系。
Diabetes Care. 2020 Jul;43(7):1399-1407. doi: 10.2337/dc20-0660. Epub 2020 May 14.
9
Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes.COVID-19 合并 2 型糖尿病患者的血糖控制与结局的相关性。
Cell Metab. 2020 Jun 2;31(6):1068-1077.e3. doi: 10.1016/j.cmet.2020.04.021. Epub 2020 May 1.
10
60 years of metformin use: a glance at the past and a look to the future.二甲双胍使用60年：回顾过去，展望未来。
Diabetologia. 2017 Sep;60(9):1561-1565. doi: 10.1007/s00125-017-4343-y.
Zotero 插件