制定用于检查系统性硬化症上肢康复结果的肌肉骨骼超声方案。
Development of a Musculoskeletal Ultrasound Protocol to Examine Upper Extremity Rehabilitation Outcomes in Systemic Sclerosis.
作者信息
Murphy Susan L, Krause Donnamarie, Roll Shawn C, Gandikota Girish, Barber Mary, Khanna Dinesh
机构信息
Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.
VA Ann Arbor Health Care System, Ann Arbor, MI, Geriatric Research Education and Clinical Center (GRECC).
出版信息
J Diagn Med Sonogr. 2021 Jan;37(1):13-23. doi: 10.1177/8756479320965210. Epub 2020 Nov 22.
OBJECTIVES
This study developed a musculoskeletal ultrasound (MSUS) protocol to evaluate rehabilitation outcomes in systemic sclerosis.
MATERIALS & METHODS: Three MSUS methods (grey scale, Doppler, strain elastography) and two acquisition techniques (long versus short axis; transducer on skin versus floating on gel) were examined in the forearm before and after rehabilitation treatment. For grey-scale, tissue thickness measures, intra- and inter-rater reliability were calculated (ICCs), and paired t-tests examined differences among techniques.
RESULTS
Five people with diffuse cutaneous systemic sclerosis participated. The most valid and reliable grey-scale technique was with the transducer in long-axis, floating on gel. Doppler and strain elastography did not detect changes. Both dermal and subcutaneous thickness measurement error was small; intra- and inter-rater reliability was good to excellent. Preliminary data indicate that treatment may lead to dermal thinning.
CONCLUSION
A replicable protocol was established and may be an adjunct to rehabilitation outcome measurement in systemic sclerosis.
目的
本研究制定了一种肌肉骨骼超声（MSUS）方案，以评估系统性硬化症的康复效果。
材料与方法
在康复治疗前后，对前臂采用三种MSUS方法（灰阶、多普勒、应变弹性成像）和两种采集技术（长轴与短轴；换能器置于皮肤上与悬浮于凝胶上）进行检查。对于灰阶，计算组织厚度测量值、评估者内和评估者间的可靠性（组内相关系数），并采用配对t检验检查技术之间的差异。
结果
五名弥漫性皮肤系统性硬化症患者参与研究。最有效且可靠的灰阶技术是将换能器置于长轴、悬浮于凝胶上。多普勒和应变弹性成像未检测到变化。真皮和皮下组织厚度测量误差均较小；评估者内和评估者间的可靠性良好至优秀。初步数据表明治疗可能导致真皮变薄。
结论
建立了一种可重复的方案，可能成为系统性硬化症康复效果测量的辅助手段。
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