Transcriptomic Signature of Asthma-Chronic Obstructive Pulmonary Disease Overlap in Whole Blood.
作者信息
Saferali Aabida, Yun Jeong H, Lee Sool, Chase Robert P, Bowler Russell P, Castaldi Peter J, Hersh Craig P
机构信息
Brigham and Women's Hospital, Boston, Massachusetts.
Harvard Medical School, Boston, Massachusetts, and.
出版信息
Am J Respir Cell Mol Biol. 2021 Feb;64(2):268-271. doi: 10.1165/rcmb.2020-0382LE.
Abstract
摘要
相似文献
1
Transcriptomic Signature of Asthma-Chronic Obstructive Pulmonary Disease Overlap in Whole Blood.全血中哮喘-慢性阻塞性肺疾病重叠综合征的转录组特征
Am J Respir Cell Mol Biol. 2021 Feb;64(2):268-271. doi: 10.1165/rcmb.2020-0382LE.
2
Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease.哮喘-慢性阻塞性肺疾病重叠综合征。慢性阻塞性肺疾病中2型炎症基因组特征的临床相关性。
Am J Respir Crit Care Med. 2015 Apr 1;191(7):758-66. doi: 10.1164/rccm.201408-1458OC.
3
Transcriptome-based Signatures: The Future Biomarkers in Obstructive Pulmonary Diseases Such as Asthma and Chronic Obstructive Pulmonary Disease?基于转录组的特征：会成为哮喘和慢性阻塞性肺疾病等阻塞性肺病未来的生物标志物吗？
Am J Respir Crit Care Med. 2022 Jan 15;205(2):139-140. doi: 10.1164/rccm.202110-2353ED.
4
Transcriptome analysis of sputum cells reveals two distinct molecular phenotypes of "asthma and chronic obstructive pulmonary disease overlap" in the elderly.痰细胞转录组分析揭示老年人“哮喘和慢性阻塞性肺疾病重叠”的两种不同分子表型。
Eur J Med Res. 2022 Oct 28;27(1):215. doi: 10.1186/s40001-022-00861-2.
5
Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma.COPD 与哮喘患者的血嗜酸性粒细胞计数与气道上皮转录组的关系。
Allergy. 2020 Feb;75(2):370-380. doi: 10.1111/all.14016. Epub 2019 Sep 10.
6
Genetic Determinants in Airways Obstructive Diseases: The Case of Asthma Chronic Obstructive Pulmonary Disease Overlap.气道阻塞性疾病的遗传决定因素：哮喘-慢性阻塞性肺疾病重叠的案例。
Immunol Allergy Clin North Am. 2022 Aug;42(3):559-573. doi: 10.1016/j.iac.2022.03.003. Epub 2022 Jun 30.
7
Integrating murine gene expression studies to understand obstructive lung disease due to chronic inhaled endotoxin.整合鼠基因表达研究以了解慢性吸入内毒素导致的阻塞性肺疾病。
PLoS One. 2013 May 13;8(5):e62910. doi: 10.1371/journal.pone.0062910. Print 2013.
8
Differential expression of microRNAs in exhaled breath condensates of patients with asthma, patients with chronic obstructive pulmonary disease, and healthy adults.哮喘患者、慢性阻塞性肺疾病患者及健康成年人呼出气冷凝物中微小RNA的差异表达
J Allergy Clin Immunol. 2013 Jul;132(1):217-9. doi: 10.1016/j.jaci.2013.03.006. Epub 2013 Apr 28.
9
Expression profiling of miRNA-145 and miRNA-338 in serum and sputum of patients with COPD, asthma, and asthma-COPD overlap syndrome phenotype.慢性阻塞性肺疾病（COPD）、哮喘及哮喘-COPD重叠综合征表型患者血清和痰液中miRNA-145与miRNA-338的表达谱分析
Int J Chron Obstruct Pulmon Dis. 2017 Jun 23;12:1811-1817. doi: 10.2147/COPD.S130616. eCollection 2017.
引用本文的文献
1
Distinct physiological, transcriptomic, and imaging characteristics of asthma-COPD overlap compared to asthma and COPD in smokers.与吸烟者中的哮喘和慢性阻塞性肺疾病（COPD）相比，哮喘-COPD重叠综合征的独特生理、转录组学和影像学特征。
EBioMedicine. 2024 Dec;110:105453. doi: 10.1016/j.ebiom.2024.105453. Epub 2024 Nov 23.
2
ACDC: a general approach for detecting phenotype or exposure associated co-expression.ACDC：一种检测与表型或暴露相关的共表达的通用方法。
Front Med (Lausanne). 2023 May 19;10:1118824. doi: 10.3389/fmed.2023.1118824. eCollection 2023.
3
Genetic Determinants in Airways Obstructive Diseases: The Case of Asthma Chronic Obstructive Pulmonary Disease Overlap.气道阻塞性疾病的遗传决定因素：哮喘-慢性阻塞性肺疾病重叠的案例。
Immunol Allergy Clin North Am. 2022 Aug;42(3):559-573. doi: 10.1016/j.iac.2022.03.003. Epub 2022 Jun 30.
4
Blood RNA sequencing shows overlapping gene expression across COPD phenotype domains.血液 RNA 测序显示 COPD 表型领域存在重叠的基因表达。
Thorax. 2022 Feb;77(2):115-122. doi: 10.1136/thoraxjnl-2020-216401. Epub 2021 Jun 24.
本文引用的文献
1
Immunoglobulin E as a Biomarker for the Overlap of Atopic Asthma and Chronic Obstructive Pulmonary Disease.免疫球蛋白E作为特应性哮喘与慢性阻塞性肺疾病重叠的生物标志物
Chronic Obstr Pulm Dis. 2020 Jan;7(1):1-12. doi: 10.15326/jcopdf.7.1.2019.0138.
2
Bitter Taste Receptors for Asthma Therapeutics.用于哮喘治疗的苦味受体
Front Physiol. 2019 Jul 16;10:884. doi: 10.3389/fphys.2019.00884. eCollection 2019.
3
Clinical Approach to the Therapy of Asthma-COPD Overlap.临床治疗哮喘-COPD 重叠综合征的方法。
Chest. 2019 Jan;155(1):168-177. doi: 10.1016/j.chest.2018.07.028. Epub 2018 Aug 2.
4
Genetic regulation of methylation and IL1RL1-a protein levels in asthma.哮喘中甲基化和 IL1RL1-a 蛋白水平的遗传调控。
Eur Respir J. 2018 Mar 8;51(3). doi: 10.1183/13993003.01377-2017. Print 2018 Mar.
5
asthma risk variants regulate airway type 2 inflammation.哮喘风险变异调控气道 2 型炎症。
JCI Insight. 2016 Sep 8;1(14):e87871. doi: 10.1172/jci.insight.87871.
6
Targeting sphingosine-1-phosphate signaling in lung diseases.针对肺病中的1-磷酸鞘氨醇信号通路
Pharmacol Ther. 2016 Dec;168:143-157. doi: 10.1016/j.pharmthera.2016.09.008. Epub 2016 Sep 13.
7
Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease.哮喘-慢性阻塞性肺疾病重叠综合征。慢性阻塞性肺疾病中2型炎症基因组特征的临床相关性。
Am J Respir Crit Care Med. 2015 Apr 1;191(7):758-66. doi: 10.1164/rccm.201408-1458OC.
8
limma powers differential expression analyses for RNA-sequencing and microarray studies.limma为RNA测序和微阵列研究提供差异表达分析的动力。
Nucleic Acids Res. 2015 Apr 20;43(7):e47. doi: 10.1093/nar/gkv007. Epub 2015 Jan 20.
9
The clinical and genetic features of COPD-asthma overlap syndrome.慢性阻塞性肺疾病-哮喘重叠综合征的临床和遗传特征。
Eur Respir J. 2014 Aug;44(2):341-50. doi: 10.1183/09031936.00216013. Epub 2014 May 29.
10
voom: Precision weights unlock linear model analysis tools for RNA-seq read counts.voom：精确权重为RNA测序读数计数解锁线性模型分析工具。
Genome Biol. 2014 Feb 3;15(2):R29. doi: 10.1186/gb-2014-15-2-r29.
Zotero 插件